Abstract
The objective of this study was to investigate the association between ambient particulate matters (PMs) and chronic obstructive pulmonary disease (COPD) mortality. generalized additive mixed model was employed to investigate the effects of ambient fine and coarse PMs on COPD mortality using 13,066 deaths from 2014 to 2016 among six cities in Zhejiang Province in Southeastern China. The daily average death count due to COPD was 3, varying from 1 to 7 among six cities. The daily 24-h mean concentrations were diverse among cities, from 29.7 to 56.8 μg/m3 for PM2.5, 16.7 to 30.3 μg/m3 for PM2.5–10, and 50.3 to 87.1 μg/m3 for PM10, respectively. The analysis showed that daily exposure to PM2.5 and PM10 was associated with increased mortality due to COPD and that weak effects were observed between PM2.5–10 and COPD mortality. Our results provided solid evidence that the fine particles in air pollution have stronger functions on adverse health effects other than coarser particles in Southeastern China, which may be considered as a potential clinic target in PM-associated COPD.
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Acknowledgements
The authors would like to acknowledge the Zhejiang Environmental Institute and Zhejiang Meteorological Administration for providing the dataset.
Funding
This work has been supported by the National Natural Science Foundation of China (81300641, 81502786, 81670833), Medical Scientific Research Foundation of Zhejiang Province, China (2019KYA053, 2020KY093, 2020KY514, 2020KY516), Science and Technology Program of Zhejiang (2014C03025), Natural Science Foundation of Zhejiang Province (LQ14H260003), Zhejiang Province Key Research and Development Program (2015C03042, 2019C03091), and the Fundamental Research Funds for the Central Universities (2019QNA7026).
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Zhijian Chen, Qiuli Fu, and Zhe Mo: conceptualization, methodology, software, data curation, and writing—original draft preparation. Zhifang Wang and Xuejiao Pan: data curation and writing—original draft preparation. Guangming Mao, Peiwei Xu, and Dandan Xu: visualization and investigation. Xiaoming Lou, Xiaofeng Wang, and Yuanqun Feng: supervision. Lizhi Wu: software and validation. Yuan Chen: writing—reviewing and editing.
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Chen, Z., Fu, Q., Mao, G. et al. Increasing mortality caused by chronic obstructive pulmonary disease (COPD) in relation with exposure to ambient fine particulate matters: an analysis in Southeastern China. Environ Sci Pollut Res 28, 53605–53613 (2021). https://doi.org/10.1007/s11356-021-14009-y
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DOI: https://doi.org/10.1007/s11356-021-14009-y