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Comparison of normal and dusty day impacts on fractional exhaled nitric oxide and lung function in healthy children in Ahvaz, Iran

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Abstract

Children are the vulnerable group at risk of adverse health effects related to air pollution due to dust storm in Ahvaz. The purpose of this study was to compare the values of fractional exhaled nitric oxide (FENO) and lung functions as parameters of adverse health effects of particulate matter (PM) in dusty and normal (non-dusty) days in elementary schoolchildren. The study was conducted among elementary school students in Ahvaz. The healthy elementary schoolchildren (N = 105) were selected from different districts for FENO and lung function sampling during the dusty and normal days. The values of PM10 and PM2.5 during dusty days were higher than during normal days. Mean values of FENO during the normal and dusty days were 14.23 and 20.3 ppb, respectively, and the difference between these values was statistically significant (p < 0.05). Lung function results showed a statistically significant difference between the mean values of forced vital capacity during the dusty and normal days (p < 0.05). The results revealed a significant difference both in the values of inflammatory biomarker and in the lung function tests in dusty and normal days. Based on our results, fractional exhaled nitric oxide could be a useful short-term biomarker of particulate pollution effect coupled with spirometry.

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Acknowledgments

This study was part of a funded Ph.D thesis of Mehdi Vosoughi, a student at Ahvaz Jundishapur University of Medical Sciences (AJUMS). AJUMS provided the financial support of this study (ETRC-9443). The authors also thank the National Oceanic Atmospheric Administration (NOAA) for providing a web-based HYSPLIT to allow us to do more workwise in this respect.

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Authors and Affiliations

  1. Environmental Technologies Research Center, Department of Environmental Health Engineering, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

    Abdolkazem Neisi, Gholamreza Goudarzi, Afshin Takdastan, Ali Akbar Babaei & Kambiz Ahmadi Ankali

  2. Student Research Committee, Department of Environmental Health Engineering, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

    Mehdi Vosoughi

  3. Department of Environmental Health Engineering, School of Public Health, Ardabil University of Medical Sciences, Ardabil, Iran

    Mehdi Vosoughi

  4. Department of Internal Medicine, Division of Pulmonology, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

    Esmaeil Idani & Maryam Haddadzadeh Shoshtari

  5. Air Pollution and Respiratory Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

    Esmaeil Idani, Gholamreza Goudarzi & Maryam Haddadzadeh Shoshtari

  6. Department of Statistics and Epidemiology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

    Kambiz Ahmadi Ankali & Iman Mirr

  7. Department of Occupational and Environmental Health Engineering, School of Public Health, Ardabil University of Medical Sciences, Ardabil, Iran

    Sadegh Hazrati

  8. Master of Environmental Engineering, School of Science Water Engineering, Shahid Chamran University of Ahvaz, Ahvaz, Iran

    Heidar Maleki

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  1. Abdolkazem Neisi
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  2. Mehdi Vosoughi
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  3. Esmaeil Idani
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  4. Gholamreza Goudarzi
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  7. Kambiz Ahmadi Ankali
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  8. Sadegh Hazrati
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  9. Maryam Haddadzadeh Shoshtari
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  10. Iman Mirr
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  11. Heidar Maleki
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Correspondence to Mehdi Vosoughi.

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Compliance with ethical standards

This study was approved by the research ethics committee of Ahvaz Jundishapur University of Medical Sciences (IR.AJUMS.REC.1394.629).

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The authors declare that they have no conflicts of interest.

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Responsible editor: Philippe Garrigues

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Neisi, A., Vosoughi, M., Idani, E. et al. Comparison of normal and dusty day impacts on fractional exhaled nitric oxide and lung function in healthy children in Ahvaz, Iran. Environ Sci Pollut Res 24, 12360–12371 (2017). https://doi.org/10.1007/s11356-017-8853-4

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