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Efficacy of high-flow nasal oxygen during drug-induced sleep endoscopy in patients with obstructive sleep apnea

  • Sleep Breathing Physiology and Disorders • Original Article
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Abstract

Purpose

High-flow nasal oxygenation (HFNO) can provide a low level of continuous positive airway pressure and alveolar recruitment. We aimed to compare the efficacy of pre-oxygenation with HFNO and low-flow nasal oxygenation (LFNO) during drug-induced sleep endoscopy (DISE).

Methods

In the LFNO group, preoxygenation was performed for 10 min at 3 L·min–1. In the HFNO group, preoxygenation was performed for 10 min at 30 L·min–1 at a fraction of inspired oxygen of 100% using the Optiflow device. From the start of sedative administration to the end of DISE, vital signs were monitored continuously. The primary outcome was the lowest oxygen saturation (SpO2) during DISE.

Results

Of 24 patients enrolled, 12 were randomly assigned to the LFNO and 12 to the HFNO groups. The prevalence of hypoxia events was 75% in the LFNO group and 58% in the HFNO group. The difference in lowest oxygen saturation between the two groups was not significant between the two groups (P=0.665). The lowest SpO2 during all procedures was comparable between the two groups (86.8 ± 6.5% in the LFNO group and 87.2 ± 8.0% in the HFNO group; P=0.912).

Conclusions

The findings suggest that HFNO may not be superior to LFNO as a preoxygenation tool to prevent hypoxia during DISE.

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Data, material, and/or code availability

The data presented in this study are available on request from the corresponding author. The data are not publicly available due to privacy.

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Authors and Affiliations

  1. Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, South Korea

    Sujung Park, So Yeon Kim & Hyun Joo Kim

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Contributions

Conceptualization, So Yeon Kim, Hyun Joo Kim; methodology, Sujung Park; software, Sujung Park; validation, Sujung Park; formal analysis, Sujung Park; data curation, Hyun Joo Kim, Sujung Park; writing—original draft preparation, Sujung Park; writing—review and editing, Sujung Park, So Yeon Kim, Hyun Joo Kim; visualization, Sujung Park, Hyun Joo Kim; supervision, Hyun Joo Kim; project administration, Hyun Joo Kim; All authors have read and agreed to the published version of the manuscript.

Corresponding author

Correspondence to Hyun Joo Kim.

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Ethics approval

This study was approved by the university’s institutional review board (IRB) (IRB no.: 4-2018-0923).

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Written informed consent was obtained from all individuals participating in this trial.

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The authors declare no competing interests.

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Park, S., Kim, S.Y. & Kim, H.J. Efficacy of high-flow nasal oxygen during drug-induced sleep endoscopy in patients with obstructive sleep apnea. Sleep Breath 27, 1779–1785 (2023). https://doi.org/10.1007/s11325-023-02785-5

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  • DOI: https://doi.org/10.1007/s11325-023-02785-5

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