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Sleep-disordered breathing in children with craniosynostosis

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Abstract

Background

Syndromic craniosynostosis (SC) is associated with a high prevalence of sleep-disordered breathing (SDB). However, it remains unclear whether non-syndromic craniosynostosis (NSC) is associated with an increased risk for SDB.

Setting

This study was conducted at a tertiary referral pediatric medical center.

Methods

A prospective polysomnographic (PSG) evaluation was conducted of all children diagnosed with craniosynostosis over a 3-year period and who had not undergone previous PSG for SDB-related symptoms.

Results

Among 14 children fulfilling inclusion criteria, 10 had NSC and 4 were diagnosed with SC (Crouzon syndrome). SDB was present in 50 % of the NSC and in 75 % of SC. No associations emerged between the number of sutures affected and the presence of SDB.

Conclusions

SDB is highly prevalent not only in SC but also among asymptomatic children with NSC. The diagnosis of NSC should prompt a diagnostic PSG as a routine component of the clinical evaluation, and PSG findings may aid in the formulation of decisions regarding timing and need for surgical interventions.

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Acknowledgments

This work was supported by the College of Medicine Research Centre (CMRC), King Saud University, Riyadh, KSA.

Conflict of interest

There are no conflicts of interest to declare.

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Authors and Affiliations

  1. Division of Pediatric Respiratory Medicine, Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia

    Muslim M. Alsaadi & Shaikh M. Iqbal

  2. Division of Neurosurgery, Surgery Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia

    Essam A. Elgamal

  3. Division of Pediatric Neurology, Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia

    Mustafa A. Salih

  4. Department of Pediatrics, Comer Children’s Hospital, The University of Chicago, 5721 S. Maryland Avenue, MC 8000, Suite K-160, Chicago, IL, 60637, USA

    David Gozal

Authors
  1. Muslim M. Alsaadi
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  2. Shaikh M. Iqbal
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  3. Essam A. Elgamal
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  4. Mustafa A. Salih
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  5. David Gozal
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Corresponding author

Correspondence to David Gozal.

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Alsaadi, M.M., Iqbal, S.M., Elgamal, E.A. et al. Sleep-disordered breathing in children with craniosynostosis. Sleep Breath 17, 389–393 (2013). https://doi.org/10.1007/s11325-012-0706-2

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  • DOI: https://doi.org/10.1007/s11325-012-0706-2

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