Abstract
Enterococcus hirae is rarely collected from man, while it is a common pathogen in mammals and birds. We describe the first isolation of the organism (strain DSM 27815) from human umbilical cord blood (UCB), thus emphasizing the risk of contamination of UCB units for clinical use. In this context, we also highlight the importance of an extensive training of the collecting personnel as to the observance of the disinfection protocol ensuring UCB units sterility.
This is a preview of subscription content, log in via an institution to check access.
References
Ballen KK, Gluckman E, Broxmeyer HE (2013) Umbilical cord blood transplantation: the first 25 years and beyond. Blood 122:491–498
Chan TS, Wu MS, Suk FM, Chen CN, Chen YF, Hou YH, Lien GS (2012) Enterococcus hirae-related acute pyelonephritis and cholangitis with bacteremia: an unusual infection in humans. Kaohsiung J Med Sci 28:111–114
Clark P, Trickett A, Stark D, Vowels M (2012) Factors affecting microbial contamination rate of cord blood collected for transplantation. Transfusion 52:1770–1777
Foulquié Moreno MR, Sarantinopoulos P, Tsakalidou E, De Vuyst L (2006) The role and application of enterococci in food and health. Int J Food Microbiol 106:1–24
Guo CJ, Gao Y, Hou D, Shi DY, Tong XM, Shen D, Xi YM, Wang JF (2011) Preclinical transplantation and safety of HS/PCs expanded from human umbilical cord blood. World J Stem Cells 3:43–52
International Standards NetCord-FACT for Cord Blood Collection, Banking, Selection and Release for Administration, 5th edn
Savini V, Catavitello C, Astolfi D, Balbinot A, Masciarelli G, Pompilio A, Quaglietta AM, Accorsi P, Di Bonaventura G, D’Amario C, D’Antonio D, Iacone A (2010) Bacterial contamination of platelets and septic transfusions: review of the literature and discussion on recent patents about biofilm treatment. Recent Pat Antiinfect Drug Discov 5:168–176
Savini V, Gherardi G, Astolfi D, Polilli E, Dicuonzo G, D’Amario C, Fazii P, D’Antonio D (2012) Insights into airway infections by enterococci: a review. Recent Pat Antiinfect Drug Discov 7:36–44
Talarmin JP, Pineau S, Guillouzouic A, Boutoille D, Giraudeau C, Reynaud A, Lepelletier D, Corvec S (2011) Relapse of Enterococcus hirae prosthetic valve endocarditis. J Clin Microbiol 49:1182–1184
Tan C-K, Lai C–C, Wang J-Y, Lin S-H, Liao C-H, Huang Y-T, Wang C-Y, Lin H-I, Hsueh P-R (2010) Bacteremia caused by non-faecalis and non-faecium enterococcus species at a Medical center in Taiwan, 2000 to 2008. J Infect 61:34–43
Conflict of interest
None.
Author information
Authors and Affiliations
Corresponding author
Additional information
Giovanni Gherardi, Tiziana Bonfini and Vincenzo Savini (in alphabetical order) contributed equally to this work.
Rights and permissions
About this article
Cite this article
Savini, V., Bonfini, T., Marrollo, R. et al. Enterococcus hirae: a zoonotic microorganism in human umbilical cord blood. World J Microbiol Biotechnol 30, 1423–1426 (2014). https://doi.org/10.1007/s11274-013-1537-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11274-013-1537-4