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Head-to-head comparison of prostatic urethral lift and water vapor thermal therapy for the treatment of symptomatic benign prostatic hyperplasia: a real-life study

  • Urology - Original Paper
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Abstract

Purpose

This study aimed at reporting a head-to-head comparison between water vapor thermal therapy using the Rezūm™ system and prostatic urethral lift using the Urolift™ system in men with lower urinary tract symptoms due to benign prostatic hyperplasia (BPH).

Patients and methods

From December 2017 to November 2019, consecutive patients who underwent Rezūm™ and Urolift™ procedures in two urology centers have been retrospectively considered. Only patients with a prostate size less than 80 mL were included. We used the PSM method to adjust baseline differences between both groups. The co-primary endpoint included the change in International Prostate Symptom Score (IPSS) and IPSS- quality of life (QoL) from baseline to 12 months.

Results

A total of 61 (52.1%) and 56 (47.9%) patients underwent Rezum™ and Urolift™ procedures, respectively. After PSM adjustment, 24 patients were included in both groups. No serious adverse events occurred (> Clavien II) in both groups. At 12 months, higher IPSS improvement was observed in the Rezum™ group (median:4 [IQR 3–5]) than in the Urolift™ group (median:8 [IQR 7–12]), without statistical difference (p = 0.08). The improvement in term of QoL at 12 m was similar (p = 0.43). The retreatment rates were 25% (Urolift™) and 8.3% (Rezum™), p = 0.24. Erection and ejaculatory function scores did not change significantly in either treatment group. Results in the full cohort showed that Rezum™ appeared to deliver greater improvements for IPSS and IPSS-QoL (p < 0.001 and p = 0.006, respectively) and lower reintervention rate (p = 0.006) than Urolift™.

Conclusions

In this small retrospective study, our results indicate that both Rezum™ and Urolift™ provide a clinically significant improvement in symptoms and QoL, although some of these improvements were greater in the Rezum™ arm. Future studies are needed to definitively assess which treatment would be best suited for each patient.

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References

  1. Gravas S, Cornu JN, Gacci M, Gratzke C, Herrmann TRW, Mamoulakis C et al (2020) EAU guidelines on non-neurogenic male lower urinary tract symptoms (LUTS), incl. European Association of Urology, Benign prostatic obstruction (BPO)

  2. Reich O, Gratzke C, Bachmann A et al (2008) Morbidity, mortality and early outcome of transurethral resection of the prostate: a prospective multicenter evaluation of 10,654 patients. J Urol 180:246–249

    Article  Google Scholar 

  3. Cornu JN, Ahyai S, Bachmann A et al (2015) A systematic review and meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic obstruction: an update. Eur Urol 67:1066–1096

    Article  Google Scholar 

  4. Madersbacher S, Roehrborn CG, Oelke M (2020) The role of novel minimally invasive treatments for lower urinary tract symptoms associated with benign prostatic hyperplasia. BJU Int 126(3):317–326

    Article  Google Scholar 

  5. Suarez-Ibarrola R, Miernik A, Gratzke C, Schoeb DS (2020) Reasons for new MIS. Let’s be fair: iTIND. World J Urol, Urolift and Rezūm. https://doi.org/10.1007/s00345-020-03453-z

    Book  Google Scholar 

  6. Dornbier R, Pahouja G, Branch J, McVary KT (2020) The new american urological association benign prostatic hyperplasia clinical guidelines: 2019 Update. Curr Urol Rep 21(9):32

    Article  Google Scholar 

  7. Roehrborn CG et al (2017) Five year results of the prospective randomized controlled prostatic urethral LIFT study. Can J Urol 24(3):8802–8813

    PubMed  Google Scholar 

  8. Rukstalis D et al (2016) 24-month durability after crossover to the prostatic urethral lift from randomised, blinded sham. BJU Int 118(Suppl 3):14–22

    Article  Google Scholar 

  9. McVary KT, Rogers T, Roehrborn CG (2019) Rezum water vapor thermal therapy for lower urinary tract symptoms associated with benign prostatic hyperplasia: 4-year results from randomized con- trolled study. Urology 126:171–179

    Article  Google Scholar 

  10. Sonksen J et al (2015) Prospective, randomized, multinational study of prostatic urethral lift versus transurethral resection of the prostate: 12-month results from the BPH6 study. Eur Urol 68(4):643–652

    Article  Google Scholar 

  11. Gratzke C et al (2017) Prostatic urethral lift vs transurethral resection of the prostate: 2-year results of the BPH6 prospective, multicentre, randomized study. BJU Int 119(5):767–775

    Article  Google Scholar 

  12. Alegorides C, Fourmarier M, Eghazarian C, Lebdai S, Chevrot A, Droupy S (2020) Treatment of benign prostate hyperplasia using the Rezum® water vapor therapy system: results at one year. Prog Urol S1166–7087(20):30166–30174

    Google Scholar 

  13. Beurrier S, Peyromaure M, Belas O, Barry N, Delongchamps. (2015) Are the UroLift(®) implants an alternative for the treatment of benign prostatic hyperplasia? Short-term results and predictive factors of failure. Prog Urol 25(9):523–529

    Article  CAS  Google Scholar 

  14. Mynderse LA, Hanson D, Robb RA et al (2015) Rezūm system water vapor treatment for lower urinary tract symptoms/benign prostatic hyperplasia: validation of convective thermal energy transfer and characterization with magnetic resonance imaging and 3-dimensional renderings. Urology 86(1):122–127

    Article  Google Scholar 

  15. McNicholas T, Woo H, Chin P et al (2013) Minimally invasive prostatic urethral lift: surgical technique and multinational experience. Eur Urol 64:292–299

    Article  Google Scholar 

  16. Clavien PA, Sanabria JR, Strasberg SM (1992) Proposed classification of complications of surgery with examples of utility in cholecystectomy. Surgery 111:518–526

    CAS  PubMed  Google Scholar 

  17. Userovici M, Ochoa A, Anract J, Beurrier S, Peyromaure M, Barry N, Delongchamps. (2020) Prostatic urethral lift using Urolift® system for benign prostatic hyperplasia: 7years experience. Prog Urol 30(3):147–154

    Article  CAS  Google Scholar 

  18. Tanneru K, Jazayeri SB, Alam MU et al (2021) An Indirect Comparison of Newer Minimally Invasive Treatments for Benign Prostatic Hyperplasia: a Network Meta-Analysis Model. J Endourol 35(4):409–416

    Article  Google Scholar 

  19. Roehrborn CG, Rukstalis DB, Barkin J et al (2015) Three year results of the prostatic urethral L.I.F.T. study. Can J Urol 22:7772–7782

    PubMed  Google Scholar 

  20. McVary KT, Roehrborn CG (2018) Three-year outcomes of the prospective, randomized controlled rezūm system study: convective radiofrequency thermal therapy for treatment of lower urinary tract symptoms due to benign prostatic hyperplasia. Urology 111:1–9

    Article  Google Scholar 

  21. Darson MF, Alexander EE, Schiffman ZJ et al (2017) Procedural techniques and multicenter postmarket experience using minimally invasive convective radiofrequency thermal therapy with Rezūm system for treatment of lower urinary tract symptoms due to benign prostatic hyperplasia. Res Reports Urol 21(9):159–168

    Article  Google Scholar 

  22. Rukstalis D, Grier D, Stroup SP et al (2019) Prostatic Urethral Lift (PUL) for obstructive median lobes: 12 month results of the MedLift Study. Prostate Cancer Prostatic Dis 22(3):411–419

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Urology, Aix-en-Provence Hospital, Aix en Provence, France

    Michael Baboudjian, Marc Fourmarier & Camille Alegorides

  2. Department of Urology and Kidney Transplantation, La Conception Hospital, AixMarseille University, APHM, Marseille, France

    Michael Baboudjian & Bastien Gondran-Tellier

  3. Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria

    Benjamin Pradere

  4. Department of Urology, Cochin Hospital, APHP, University of Paris Descartes, Paris, France

    Mickael Userovici & Nicolas Barry Delongchamps

Authors
  1. Michael Baboudjian
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  2. Marc Fourmarier
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  3. Bastien Gondran-Tellier
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  4. Benjamin Pradere
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  5. Mickael Userovici
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  6. Camille Alegorides
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  7. Nicolas Barry Delongchamps
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Correspondence to Michael Baboudjian.

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Baboudjian, M., Fourmarier, M., Gondran-Tellier, B. et al. Head-to-head comparison of prostatic urethral lift and water vapor thermal therapy for the treatment of symptomatic benign prostatic hyperplasia: a real-life study. Int Urol Nephrol 53, 1757–1763 (2021). https://doi.org/10.1007/s11255-021-02899-3

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  • DOI: https://doi.org/10.1007/s11255-021-02899-3

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