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Daily physical activity in patients on chronic haemodialysis and its relation with fatigue and depressive symptoms

  • Nephrology - Original Paper
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Abstract

Objective

Fatigue and depressed mood are considered main impediments to physical activity in haemodialysis (HD) patients. A better understanding of their interrelationships is crucial to develop effective therapies. Moreover, measurement of daily physical activity (DPA) in HD patients is tricky, as it is usually assessed by subjective self-report questionnaires. Therefore, we aimed to objectively measure sponteanous DPA with motion sensors and to explore its relation with fatigue and depressive symptoms.

Methods

DPA was assessed for seven consecutive days in 37 HD patients based on their daily step count measured with the SenseWear™ Armband. The Fatigue Severity Scale (FSS) and Beck Depression Inventory-II (BDI-II) were administered to evaluate fatigue and depressed mood.

Results

Median DPA was 2424 steps/day, (IQR:892–4545). In 81% of subjects, DPA felt within a sedentary lifestyle classification, as they made < 5.000 steps/day. DPA did not correlate with fatigue (rs = 0.04, p = 0.832), and did not significantly differ between patients categorized as clinically fatigued (n = 23, FSS ≥ 4) or not (n = 14, FSS < 4) (p = 0.654, d = 0.20). Although low-depressed subjects (n = 19, BDI-II ≤ 13) made on average 1.7 times more steps/day than high-depressed subjects (n = 18, BDI-II > 13) (p = 0.111, d = 0.60), depressive mood did also not correlate significantly with DPA (rs = − 0.23, p = 0.175).

Conclusion

Objective assessment of DPA with motion sensors is feasible in HD patients and allows identifying a sedentary lifestyle. Our results suggest that spontanous DPA is determined by age rather than by fatigue or mood.

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Funding

There are no financial ties to disclose.

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Authors and Affiliations

  1. Divisione Di Nefrologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

    Astrid D. H. Brys & Giovanni Gambaro

  2. Università Cattolica del Sacro Cuore, Rome, Italy

    Astrid D. H. Brys, Maurizio Bossola, Filippo Biamonte, Giovanni Gambaro & Enrico Di Stasio

  3. Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands

    Astrid D. H. Brys & Bert Lenaert

  4. School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands

    Bert Lenaert

  5. Haemodialysis Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

    Maurizio Bossola

  6. Division of Nephrology, University Hospital of Verona, Verona, Italy

    Giovanni Gambaro

  7. UOC Chimica, Biochimica E Biologia Molecolare Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

    Filippo Biamonte & Enrico Di Stasio

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  1. Astrid D. H. Brys
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Contributions

AB performed the article drafting and analysis and interpretation of data; BL performed the interpretation of data and critical revision of the article for important intellectual content; FB performed acquisition of data and revised the article; GG performed critical revision of the article for important intellectual content; MB and EDS performed conception and design, analysis and interpretation of the data and critical revision of the article for important intellectual content. All authors approved the final manuscript.

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Correspondence to Astrid D. H. Brys.

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Brys, A.D.H., Bossola, M., Lenaert, B. et al. Daily physical activity in patients on chronic haemodialysis and its relation with fatigue and depressive symptoms. Int Urol Nephrol 52, 1959–1967 (2020). https://doi.org/10.1007/s11255-020-02578-9

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  • DOI: https://doi.org/10.1007/s11255-020-02578-9

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