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Conservative/surgical treatment predictors of maternal hydronephrosis: results of a single-center retrospective non-randomized non-controlled observational study

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Abstract

Purpose

To determine the parameters that may help the clinicians decide the best suitable treatment method for the pregnant women with symptomatic hydronephrosis which will be based on the easily accessible laboratory tests, monitoring methods and clinical symptoms.

Methods

Digital data and documents of 246 pregnant women with symptomatic hydronephrosis who were hospitalized in our clinic between the dates of January 2011 and January 2016 were retrospectively evaluated. All patients were statistically evaluated in terms of age, symptomatic maximal anterior–posterior diameter of the renal pelvis (MADP), parity, C-reactive protein (CRP) level, white blood cell count (WBC), presence of pyuria, growth of urine culture, fever, serum urine and creatinine levels, visual analog scale (VAS) score of pre- and post-therapy and threatened preterm labor.

Results

The study includes a total of 211 pregnant women with symptomatic hydronephrosis. In the second and third trimester groups, the surgical treatment group statistically provided higher levels of CRP, WBC and VAS. Mean MADP in the second trimester of the conservative and surgical groups where symptomatic hydronephrosis was on the right side was 16.67 ± 4.67 and 28.68 ± 7.70 mm, respectively. Mean MADP in the third trimester group of the conservative and surgical groups where symptomatic hydronephrosis was on the right side was 16.96 ± 5.96 and 28.85 ± 7.64 mm, respectively.

Conclusions

In patients with symptomatic pregnancy hydronephrosis, the likelihood of surgical treatment for CRP levels, WBC counts and VAS is high.

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Abbreviations

DJ:

Double-J stent

BUN:

Blood urea nitrogen

WBC:

White blood cell count

CRP:

C-reactive protein

USG:

Transabdominal ultrasonography

VAS:

Visual analog scale

References

  1. Goldfarb RA, Neerhut GJ, Lederer E (1989) Management of acute hydronephrosis of pregnancy by ureteral stenting: risk of stone formation. J Urol 141:921–922

    Article  CAS  PubMed  Google Scholar 

  2. Clayton JD, Roberts JA (1972) The effect of progesterone on ureteral physiology in a primate model. J Urol 107:945–948

    Article  CAS  PubMed  Google Scholar 

  3. Waltzer WC (1981) The urinary tract in pregnancy. J Urol 125:2716

    Article  Google Scholar 

  4. Rasmussen PE, Nielsen FR (1988) Hydronephrosis during pregnancy: a literature survey. Eur J Obstet Gynecol Reprod Biol 27:249–259

    Article  CAS  PubMed  Google Scholar 

  5. Roy C, Saussine C, LeBras Y et al (1996) Assessment of painful ureterohydronephrosis during pregnancy by MR urography. Eur Radiol 6:334–338

    Article  CAS  PubMed  Google Scholar 

  6. Di Salvo DN (2003) Sonographic imaging of maternal complications of pregnancy. J Ultrasound Med 22(1):69–89

    Article  PubMed  Google Scholar 

  7. Sadan O, Berar M, Sagiv R et al (1994) Ureteric stent in severe hydronephrosis of pregnancy. Eur J Obstet Gynecol Reprod Biol 56:79–81

    Article  CAS  PubMed  Google Scholar 

  8. Jarrard DJ, Gerber GS, Lyon ES (1993) Management of acute ureteral obstruction in pregnancy utilizing ultrasound-guided placement of ureteral stents. J Urol 42:263–267

    Article  CAS  Google Scholar 

  9. Zwergel T, Lindenmeir T, Wullich B (1996) Management of acute hydronephrosis in pregnancy by ureteral stenting. Eur Urol 29:292–297

    CAS  PubMed  Google Scholar 

  10. Fainaru O, Amnog B, Gamzu R, Lessing JB, Kupferminc M (2002) The management of symptomatic hydronephrosis in pregnancy. Br J Obstet Gynecol 109:1385–1387

    Article  Google Scholar 

  11. Farr A, Ott J, Kueronya V et al (2016) The association between maternal hydronephrosis and acute flank pain during pregnancy: a prospective pilot-study. J Matern Fetal Neonatal Med 21:1–5

    Article  Google Scholar 

  12. Choi CI, Yu YD, Park DS (2016) Ureteral stent insertion in the management of renal colic during pregnancy. Chonnam Med J 52:123–127

    Article  PubMed  PubMed Central  Google Scholar 

  13. Tsai YL, Seow KM, Yieh CH, Chong KM, Hwang JL, Lin YH et al (2007) Comparative study of conservative and surgical management for symptomatic moderate and severe hydronephrosis in pregnancy: a prospective randomized study. Acta Obstet Gynecol Scand 86:1047–1050

    Article  PubMed  Google Scholar 

  14. Kavoussi LR, Albala DM, Basler JW, Apte S, Clayman RV (1992) Percutaneous management of urolithiasis during pregnancy. J Urol 148:1069–1071

    Article  CAS  PubMed  Google Scholar 

  15. D’Elia FL, Brenna RE, Brownstein PK (1982) Acute renal failure secondary to ureteral obstruction by a gravid uterus. J Urol 128:803–804

    Article  PubMed  Google Scholar 

  16. vanSonnenberg E, Casola G, Talner LB, Wittich GR, Varney RR, D’Agostino HB (1992) Symptomatic renal obstruction or urosepsis during pregnancy: treatment by sonographically guided percutaneous nephrostomy. AJR Am J Roentgenol 158:91–94

    Article  CAS  PubMed  Google Scholar 

  17. Puskar D, Balagović I, Filipović A, Knezović N, Kopjar M, Huis M et al (2001) Symptomatic physiologic hydronephrosis in pregnancy: incidence, complications and treatment. Eur Urol 39:260–263

    Article  CAS  PubMed  Google Scholar 

  18. Mandal AK, Sharma SK, Goswami AK, Hemal AK, Indudhara R (1990) The use of percutaneous diversion during pregnancy. Int J Gynecol Obstet 32:67–70

    Article  CAS  Google Scholar 

  19. Song G, Hao H, Wu X, Li X, Xiao YX, Wang G et al (2011) Treatment of renal colic with double-J stent during pregnancy: a report of 25 cases. Zhonghua Yi Xue Za Zhi 91(8):538–540

    PubMed  Google Scholar 

  20. Çeçen K, Ülker K (2014) The comparison of double J stent insertion and conservative treatment alone in severe pure gestational hydronephrosis: a case controlled clinical study. Sci World J 20:989173. doi:10.1155/2014/989173

    Google Scholar 

  21. Steel DM, Whitehead AS (1994) The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein. Immunol Today 15:80–88

    Article  Google Scholar 

  22. Jaye DL, Waites KB (1997) Clinical applications of C-reactive protein in pediatrics. Pediatr Infect Dis J 16:735–747

    Article  CAS  PubMed  Google Scholar 

  23. N’Gamba M, Lebdai S, Hasting C, Panayotopoulos P, Ammi M, Sentilhes L et al (2015) Acute renal colic during pregnancy: management and predictive factors. Can J Urol 22:7732–7738

    PubMed  Google Scholar 

  24. Angulo JC, Gaspar MJ, RodrÃ−guez N, GarcÃ−a-Tello A, Torres G, Núñez C (2010) The value of C-reactive protein determination in patients with renal colic to decide urgent urinary diversion. Urology 76:301–306

    Article  PubMed  Google Scholar 

  25. Dell’Atti L (2014) Our ultrasonographic experience in the management of symptomatic hydronephrosis during pregnancy. J Ultrasound 19:1–5

    Article  PubMed  PubMed Central  Google Scholar 

  26. Erickson LM, Nicholson SF, Lewall DB, Frischke L (1979) Ultrasound evaluation of hydronephrosis of pregnancy. J Clin Ultrasound 7:128–132

    Article  CAS  PubMed  Google Scholar 

  27. Biyani CS, Joyce AD (2002) Urolithiasis in pregnancy. II: management. BJU Int 89:819–823

    Article  CAS  PubMed  Google Scholar 

  28. Charalambous S, Fotas A, Rizk DE (2009) Urolithiasis in pregnancy. Int Urogynecol J Pelvic Floor Dysfunct 20:1133–1136

    Article  PubMed  Google Scholar 

  29. Martin JA, Hamilton BE, Osterman MJ (2016) Births in the United States. NCHS Data Brief 258:1–8

    Google Scholar 

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Authors and Affiliations

Authors

Contributions

HE helped in research concept and design and wrote the article. BA, AS and ZG finally approved the article. FO and EA were involved in the collection and/or assembly of data. UU and MED were involved in the data analysis and interpretation.

Corresponding author

Correspondence to Hakan Ercil.

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The authors of the study declare no conflict of interest.

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Ercil, H., Arslan, B., Ortoglu, F. et al. Conservative/surgical treatment predictors of maternal hydronephrosis: results of a single-center retrospective non-randomized non-controlled observational study. Int Urol Nephrol 49, 1347–1352 (2017). https://doi.org/10.1007/s11255-017-1619-6

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  • DOI: https://doi.org/10.1007/s11255-017-1619-6

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