Abstract
Aims
This case report describes a rare case of adenocarcinoma of the epididymis and the role of locoregional surgery in the therapeutic algorithm.
Clinical case
We report a case of primary adenocarcinoma of the epididymis in a 61-year-old man who was primarily examined for nodular enlargement of the head of the epididymis. Retroperitoneal lymphadenectomy which the patient underwent after radical orchiectomy revealed lymph node metastases, subsequently he received adjuvant chemotherapy. The patient remains free of disease for 20 months after surgery.
Conclusions
Primary adenocarcinoma of epididymis is a rare finding with an unfavorable prognosis in higher stages as it responds poorly to radiotherapy and chemotherapy. Our case report confirms the importance of retroperitoneal lymphadenectomy in patients with local or locoregional disease. It may be curative even in case of proven lymphadenopathy and should be performed in all patients without distant metastases.
Abbreviations
- RPLND:
-
Retroperitoneal lymphadenectomy
- CT:
-
Computed tomography
- PET:
-
Positron emission tomography
- FDG:
-
Fluorodeoxyglucose
- SUV:
-
Standardized uptake value
References
Jones MA, Young RH, Scully RE (1997) Adenocarcinoma of the epididymis. A report of four cases and review of the literature. Am J Surg Pathol 21:1474–1480
Amin MB (2005) Selected other problematic testicular and paratesticular lesions: rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumors. Mod Pathol 18:S131–S145
Petersen R, Sesterhenn I, Davis Ch (2009) Testicular adnexa. In: Petersen R, Sesterhenn I, Davis Ch (eds) Urologic pathology, 3rd edn. Lippincott Williams & Wilkins, Philadelphia, pp 419–420
Ganem JP, Jhaveri FM, Marroum M-C (1998) Primary adenocarcinoma of the epididymis: case report and review of the literature. Urology 52:904–908
Chauhan RD, Gingrich JR, Eltorky M et al (2001) The natural progression of adenocarcinoma of the epididymis. J Urol 166:608–610
Arisan S, Akbulut ON, Cakir OO et al (2004) Primary adenocarcinoma of the epididymis: case report. Int Urol Nephrol 36:77–80
Kurihara K, Oka A, Mannami M et al (1993) Papillary adenocarcinoma of the epididymis. Acta Pathol Jpn 43:440–443
Hayashi I, Satoh N, Kanemitsu N et al (2003) A case of primary adenocarcinoma of the epididymis. Acta Urol Jpn 49:341–343
Sanchez-Chapado M, Angulo JC, Haas GP (1995) Adenocarcinoma of the rete testis. Urology 46:468–4759
Donohue JP, Zachary JM, Maynard BR (1982) Distribution of nodal metastases in nonseminomatous testis cancer. J Urol 128:315–320
Acknowledgments
This study was supported by the Research plan of the Ministry of Health of the Czech Republic FUNDIN MZ0MOU2005.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Staník, M., Doležel, J., Macík, D. et al. Primary adenocarcinoma of the epididymis: the therapeutic role of retroperitoneal lymphadenectomy. Int Urol Nephrol 44, 1049–1053 (2012). https://doi.org/10.1007/s11255-012-0149-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11255-012-0149-5