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Reactivation of Hepatitis in a Bladder Cancer Patient Receiving Chemotherapy

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Abstract

Reactivation of hepatitis is a serious complication of chemotherapy in hepatitis B virus (HBV) carriers. There are many reports of this in lymphoma patients but few in urological cancer patients. A 59-year-old woman with bladder cancer who was an HBV carrier developed severe liver dysfunction after 2 cycles of chemotherapy. The diagnosis was reactivation of hepatitis. She improved with administration of lamivudine with a steroid and is currently well without disease. Care should be taken about the risk of reactivation when performing chemotherapy in HBV carriers and prophylaxis by lamivudine should be considered.

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References

  1. Seksik P, Nahon S, Lesgourgues B, Cadranel JF, Mariaud De Serre N, Lenoble M, Lahmeck P, Charoud A, Delas N (2000) Efficacity of treatment with lamivudine in two patients with severe reactivation of hepatitis B after withdrawal of chemotherapy. Gastroenterol Clin Biol 24:671–674

    PubMed  CAS  Google Scholar 

  2. Lau GKK, Liang R, Chiu EKW, Lee CK, Lam SK (1997) Hepatic events after bone marrow transplantation in patients with hepatitis B infection: a case controlled study. Bone Marrow Transplant 19:795–799

    Article  PubMed  CAS  Google Scholar 

  3. Cheng AL, Hsiung CA, Su IJ, Chen PJ, Chang MC, Taso CJ, Kao WY, Uen WC, Hsu CH, Tien HF, Chao TY, Chen LT, Jacqueline WP (2003) Steroid-free chemotherapy decreases risk of hepatitis B virus (HBV) reactivation in HBV-carriers with lymphoma. Hepatology 37:1320–1328

    Article  PubMed  CAS  Google Scholar 

  4. Simpson ND, Simpson PW, Ahmed AM, Nguyen MH, Garcia G, Keeffe EB, Ahmed A (2003) Prophylaxis against chemotherapy-induced reactivation of hepatitis B virus infection with lamivudine. J Clin Gastroenterol 37(1):68–71

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Renal and Genito-urinary Surgery, Graduate School of Medicine, Hokkaido University, Kita-15, Nishi-7, Kita-ku, Sapporo, 060-8638, Japan

    Hiroshi Higashiyama, Toru Harabayashi, Nobuo Shinohara & Katsuya Nonomura

  2. Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Kita-15, Nishi-7, Kita-ku, Sapporo, 060-8638, Japan

    Makoto Chuma & Shuhei Hige

Authors
  1. Hiroshi Higashiyama
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  2. Toru Harabayashi
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  3. Nobuo Shinohara
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  4. Makoto Chuma
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  5. Shuhei Hige
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  6. Katsuya Nonomura
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Corresponding author

Correspondence to Toru Harabayashi.

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Higashiyama, H., Harabayashi, T., Shinohara, N. et al. Reactivation of Hepatitis in a Bladder Cancer Patient Receiving Chemotherapy. Int Urol Nephrol 39, 461–463 (2007). https://doi.org/10.1007/s11255-006-9006-8

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  • DOI: https://doi.org/10.1007/s11255-006-9006-8

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