Abstract
Fibrosing cholestatic hepatitis (FCH) is an uncommon complication of renal transplantation. It is usually associated with hepatitis B and C viral infection. It is further rare in renal transplantation in absence of HBV and HCV infection. To the best of our knowledge, only three cases of FCH in renal transplantation, which were both HBV and HCV negative, have been reported to date. Out of these, two cases were diagnosed to have CMV infection and the third was attributed to azathioprin. We are presenting another case of FCH in a renal transplant recipient with CMV infection.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
SE Davies BC Portmann JG O’Grady et al. (1991) ArticleTitleHepatic histological findings after transplantation for chronic hepatitis B virus infection, including a unique pattern of fibrosing cholestatic hepatitis. Hepatology 13 150–157
LK Schluger PA Sheiner SN Thung et al. (1996) ArticleTitleSevere recurrent cholestatic hepatitis C following orthotopic liver transplantation. Hepatology 23 971–976
CH Chen PJ Chen JS Chu et al. (1994) ArticleTitleFibrosing cholestatic hepatitis in a hepatitis B surface antigen carrier after renal transplantation. Gastroenterology 107 1514–1518
JC Booth RD Goldin JL Brown et al. (1995) ArticleTitleFibrosing cholestatic hepatitis in a renal transplant recipient associated with hepatitis B virus precore mutant. J Hepatol 22 IssueID4 500–503
PWY Lam ME Wachs KA Somberg et al. (1996) ArticleTitleFibrosing choletsatic hepatitis in renal transplant recipients. Transplantation 61 378–381
F Zylerberberg F Carnot MF Mamzer et al. (1997) ArticleTitleHepatitis C virus related fibrosing cholestatic hepatitis after renal transplantation. Transplantation 63 158–160
CM Toth M Pascual RT Chung et al. (1998) ArticleTitleHepatitis C virus associated fibrosing cholestatic hepatitis after renal transplantation: response to interferon-alpha therapy. Transplantation 66 IssueID9 1254–1258
E Munoz de Bustillo A Benito F Colina et al. (2001) ArticleTitleFibrosing cholestatic hepatitis–Like syndrome in hepatitis B virus–Negative and Hepatitis C Virus–Negative Renal Transplant Recipients. Am J Kidney Dis 38 IssueID3 640–645
A Duseja R Nada N Kalra et al. (2003) ArticleTitleFibrosing cholestatic hepatitis like syndrome in a hepatitis B virus and hepatitis C virus negative renal transplant recipient: A case report with autopsy findings. Trop Gastroenterol 24 IssueID1 31–34
YS Shan PC Lee JR Wang et al. (2001) ArticleTitleFibrosing cholestatic hepatitis possibly related to persistent parvovirus B19 infection in a renal transplant recipient. Nephrol Dial Transplant 16 2420–2422
KG Benner RG Lee EB Keeffe et al. (1992) ArticleTitleFibrosing cytolytic liver failure secondary to recurrent hepatitis B after liver transplantation. Gastroenterology 103 1307–1312
V Araya J Rakela T Wright (1997) ArticleTitleHepatitis C after orthotopic liver transplantation. Gastroenterology 112 575–582
J Collier J Heathcote (1998) ArticleTitleHepatitis C viral infection in the immunosuppressed patient. Hepatology 27 2–6
JY Lau VG Bain SE Davies et al. (1992) ArticleTitleHigh-level expression of hepatitis B viral antigens in fibrosing cholestatic hepatitis. Gastroenterology 102 956–962
S Pol R Cavalcanti F Carnot et al. (1996) ArticleTitleAzathioprin hepatitis in kidney transplant recipients: A predisposing role of chronic viral hepatitis. Transplantation 61 1174–1176
E Munoz de Bustillo C Ibarrola F Colina et al. (1998) ArticleTitleFibrosing cholestatic hepatitis in hepatitis C virus infected renal transplant recipients. J Am Soc Nephrol 9 1109–1113
DA Katzka SH Saul D Jorkasky et al. (1986) ArticleTitleAzathioprin and hepatic venocclusive disease in renal transplant patients. Gastroenterology 90 446–454
F Liano F Moreno R Matesanz et al. (1989) ArticleTitleVeno-occlusive hepatic disease of the liver in renal transplantation: is azathioprin the cause? Nephron 51 509–516
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Agarwal, S.K., Kalra, V., Dinda, A. et al. Fibrosing cholestatic hepatitis in renal transplant recipient with CMV infection: A case report. Int Urol Nephrol 36, 433–435 (2004). https://doi.org/10.1007/s11255-004-6196-9
Issue Date:
DOI: https://doi.org/10.1007/s11255-004-6196-9