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Comparative effect of potentiated zinc oxide and antibiotic growth promoters on intestinal morphometry and nutrient digestibility in broiler chickens

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Abstract

The comparative effects of potentiated zinc oxide (pZnO) and antibiotic growth promoters (AGP) supplementation on intestinal morphometry and nutrient digestibility in broiler chickens were studied. Four hundred straight-run Cobb 500-day-old broiler chicks were randomly allotted to four dietary treatments replicated 10 times with 10 birds per replicate. Dietary treatments were as follows: T1: basal diets without AGP (negative control; NC), T2: basal diets with 500 g/t maduramicin 10 g and 500 g/t zinc bacitracin 150 (positive control; PC), T3: NC added with 150 g/t pZnO, and T4: PC added with 150 g/t pZnO in a 2 × 2 factorial design in RCBD. At days 18 and 35, 10 birds were randomly selected per treatment for morphometry of the duodenum, jejunum, and ileum. At day 38, eight birds per treatment were used for the nutrient digestibility study. Results showed significant interaction effects (P < 0.05) of AGP and pZnO supplementation on day 35 intestinal morphometry of duodenum’s villi height and villi height: crypt depth, and ileum’s crypt depth; apparent CODGE, AME, CP, DM, and EE. Significant differences (P < 0.05) with pZnO supplementation were only observed on feed intake and FCR of birds fed with pZnO at days 8–14 and fecal quality at days 0–7. Results of present study suggested that pZnO has the potential to replace AGPs without negatively affecting the intestinal morphometry, digestibility, and growth performance of broiler chickens.

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Funding

This research work was supported by PhilNutri Corporation and Animine.

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Authors and Affiliations

  1. Institute of Animal Science, University of the Philippines Los Baños, Los Baños, Laguna, Philippines

    B. A. Moog, A. A. Angeles & P. P. Sangel

  2. Dairy Training and Research Institute, University of the Philippines Los Baños, Los Baños, Laguna, Philippines

    A. A. Angeles

  3. Institute of Chemistry, College of Arts and Sciences, University of the Philippines Los Baños, Los Baños, Laguna, Philippines

    F. E. Merca

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  1. B. A. Moog
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  2. A. A. Angeles
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  3. F. E. Merca
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  4. P. P. Sangel
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BM and AA conceived and designed the research and conducted the experiment. All authors are involved in the analysis of the results of the experiment and write-up of the manuscript.

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Correspondence to B. A. Moog.

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Moog, B.A., Angeles, A.A., Merca, F.E. et al. Comparative effect of potentiated zinc oxide and antibiotic growth promoters on intestinal morphometry and nutrient digestibility in broiler chickens. Trop Anim Health Prod 54, 16 (2022). https://doi.org/10.1007/s11250-021-03012-7

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