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Investigation on pseudorabies prevalence in Chinese swine breeding farms in 2013–2016

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Abstract

Pseudorabies (PR) has been prevalent in Chinese swine breeding farms since the outbreak at the end of 2011. For investigating current prevalence of PR, a nationwide surveillance has been performed in this study. The swine serum samples were collected from 93, 100, 92, and 91 swine farms in China during 2013–2016, respectively. Since the extensive use of gE-deleted pseudorabies virus (PRV) vaccine, we could apply the PRV-gE antibody for determining wild-type virus infection and the PRV-gB antibody for evaluating vaccine immunization. The results were concluded as follows: (1) Nationally, the positive rate of PRV-gB was maintained at a high level (> 90%), while the positive rate of PRV-gE continued to decrease (from 22.17 to 13.14%). (2) The positive rates of PRV-gE were greatly varied in different geographical regions and swine farms (0~100%), while the positive rate of PRV-gB was generally high (> 90%). (3) The number of imported PRV attenuated vaccines were about twice that of domestic PRV attenuated vaccines, while the positive rate of PRV-gB was not significantly different (P > 0.05). (4) The performance of PR eradication developing or developed farms was better than the performance of common farms, with higher positive rate of PRV-gB (> 90%) and much lower positive rate of PRV-gE (nearly 0%).

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Acknowledgements

The authors thank for the financial support from Beijing Agriculture Innovation Consortium (BAIC-02).

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Authors and Affiliations

  1. OIE Porcine Reproductive and Respiratory Syndrome Reference Laboratory, China Animal Disease Control Center, No. 20 Maizidian Street, Chaoyang District, Beijing, 100125, China

    Yingyi Liu, Shuo Zhang, Qi Xu, Jiajun Wu, Xinyan Zhai, Shuo Li, Jing Wang, Jianqiang Ni, Lin Yuan, Xiaohui Song, Bolin Zhao, Zhi Zhou, Chuanbin Wang & Lin Yang

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  1. Yingyi Liu
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  2. Shuo Zhang
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  3. Qi Xu
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  4. Jiajun Wu
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  5. Xinyan Zhai
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  6. Shuo Li
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  7. Jing Wang
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  8. Jianqiang Ni
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  9. Lin Yuan
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  10. Xiaohui Song
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  11. Bolin Zhao
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  12. Zhi Zhou
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  13. Chuanbin Wang
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  14. Lin Yang
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Corresponding authors

Correspondence to Xinyan Zhai or Lin Yang.

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The sampling process was in line with animal welfare requirements.

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The authors declare that they have no conflict of interest.

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Liu, Y., Zhang, S., Xu, Q. et al. Investigation on pseudorabies prevalence in Chinese swine breeding farms in 2013–2016. Trop Anim Health Prod 50, 1279–1285 (2018). https://doi.org/10.1007/s11250-018-1555-1

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  • DOI: https://doi.org/10.1007/s11250-018-1555-1

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