Skip to main content
SpringerLink
Log in

Occurrence of anti-Leptospira spp. antibodies in Rhipidomys spp. from a forest fragment of the Brazilian Cerrado

  • Regular Articles
  • Published:
Tropical Animal Health and Production Aims and scope Submit manuscript

A Correction to this article was published on 07 January 2019

This article has been updated

Abstract

Leptospirosis is a zoonotic disease of world importance, and its transmission depends on the interaction between humans and animals. Given the necessity to investigate potential hosts of Leptospira spp., this study verified the prevalence of different serovars in the species of Rhipidomys spp., a widespread sigmodont rodent in Brazil. The studied population originates from a semi-evergreen forest located in the county of Uberlândia, in the state of Minas Gerais. The microscopic agglutination test (MAT) was performed with 14 serovars. Thirteen out of the 43 wild rodents captured showed a positive agglutination reaction, with a greater prevalence of the serovars Pyrogenes, Copenhageni, and Canicola. This study found a prevalence of 30.3% anti-Leptospira spp. antibodies; all positive animals were reactive to more than one serovar.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Change history

  • 07 January 2019

    The original version of this article unfortunately contains an error. Vanessa do Nascimento Ramos was not included in the original article as one of the contributors. The name is now included in the authorgroup.

  • 07 January 2019

    The original version of this article unfortunately contains an error. Vanessa do Nascimento Ramos was not included in the original article as one of the contributors. The name is now included in the authorgroup.

  • 07 January 2019

    The original version of this article unfortunately contains an error. Vanessa do Nascimento Ramos was not included in the original article as one of the contributors. The name is now included in the authorgroup.

  • 07 January 2019

    The original version of this article unfortunately contains an error. Vanessa do Nascimento Ramos was not included in the original article as one of the contributors. The name is now included in the authorgroup.

References

  • Aguiar, DM, Cavalcante, GT, Marvulo, MFV, Silva, JCR, Pinter A, Vasconcellos, SA, Morais, ZM, Labruna, MB, Camargo, LMA, Gennari, SM, 2007. Fatores de risco associados à ocorrência de anticorpos anti-Leptospira spp. em cães do município de Monte Negro, Rondônia, Amazônia Ocidental Brasileira. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 59, 70–76.

  • Alves, CJ, Andrade, JSL, Vasconcellos, SA, Morais, ZM, Azevedo, SS, Santos, FA, 2000. Avaliação dos níveis de aglutininas anti-Leptospira spp. em cães no município de Patos-PB, Brasil. Revista Brasileira de Ciência Veterinária, 7, 17–21.

  • Alves, CJ, Clementino, IJ, Oliveira, AGF, Freitas, TD, Vasconcelos, SA, Morais, ZM, 2004. Avaliação dos Níveis de aglutininas anti-Leptospira em cães de caça na Paraíba, Brasil. Revista Brasileira Ciência Veterinária, 11, 68–73.

  • Batista, CSA, Alves, CJ, Azevedo, SS, Vasconcellos, SA, Morais, ZM, Clementino, IJ, Alves, FAL, Lima, FS, Araújo-Neto, JO, 2005. Soroprevalência e fatores de risco para a leptospirose em cães de Campina Grande, Paraíba. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 57, 179–185.

  • Bonvicino, CR, Oliveira, JA, D’Andrea, PS, 2008. Guia dos Roedores do Brasil, com chave para gêneros baseadas em caracteres externos. Centro Pan-Americano de Febre Aftosa - OPAS/OMS, Rio de Janeiro, 120p.

  • Brasil, 1995. Ministério da Saúde. Fundação Nacional de Saúde. Centro Nacional de Epidemiologia. Coordenação de Controle de Zoonoses e Animais. Programa Nacional de Leptospirose. Manual de Leptospirose, 2 ed., Brasília.

  • Brasil, 2009. Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Guia de Vigilância Epidemiológica. 7 ed., Brasília, 816p.

  • Brihuega, B, Pavan, M, Cairo, F, Venzano, A, Auteri, C, Funes, D, Romero, G, Samartino, L, 2007. Pathogenic Leptospira in the kidney of Didelphys albiventris (weasel). Revista Argentina de Microbiologia, 39, 1–19.

  • Esteves, FM, Guerra­Neto, G, Girio, RJS, Silva­Vergara, ML, Carvalho, ACFB, 2005. Detecção de anticorpos para Leptospira spp. em animais e funcionários do Zoológico Municipal de Uberaba, MG. Arquivos do Instituto Biológico, 72, 283–288.

  • Furtado, LRI, Ávila, MO, Fehlberg, MFB, Teixeira, MM, Rosado, RLI, Martins, LFS, Brod, CS, 1997. Prevalência e avaliação de fatores de risco à leptospirose canina no Município de Pelotas-RS. Arquivo do Instituto Biológico, 64, 57–61.

  • Guimarães, RF, Saddi, TM, Cardoso, JR, Araújo, LBM, Araújo, EG, 2012. Estudo de patógenos de potencial zoonótico em procionídeos. Revista de Patologia Tropical, 41, 253–270.

  • Hannibal, W, Caceres, NC, 2010. Use of vertical space by small mammals in gallery forest and woodland savannah in south-western Brazil. Mammalia, 74, 247–255.

  • Hartskeerl, RA, Collares-Pereira, M, Ellis, WA, 2011. Emergence, control and re-emerging leptospirosis: dynamics of infection in the changing world. Clinical Microbiology and Infection, 17, 494–501.

  • Ibge (Instituto Brasileiro De Geografia e Estatística). Cidades: Uberlândia, MG, 2010. Available on: <http://www.ibge.gov.br/cidadesat/link.php?codmun=317020>. Access on September 24th, 2012.

  • Levett, PN, 2001. Leptospirosis. Clinical Microbiology Reviews, 14, 296–314.

  • Levett, PN, 2004. Leptospirosis: a forgotten zoonosis. Clinical and Applied Immunology Reviews, 4, 435–448.

  • Levett, PN, Haake, DA, 2010. Leptospira species (leptospirosis). In Mandell, GL, Bennett, JE, Dolin, R (eds.), Principles and practice of infectious diseases, Churchill Livingtsone Elsevier, Philadelphia, p. 3059–3065.

  • Loffler, GS, Pavan, EM, Vanasco, B, Samartino, L, Suares, O, Auteri, C, Romero, G, Briuelga, B, 2014. Genotypes of pathogenic Leptospira spp. isolated from rodents in Argentina. Memórias do Instituto Oswaldo Cruz, 109, 163–167.

  • Magalhães, DF, Silva, JA, Moreira, EC, 2006. Prevalência de aglutininas anti-Leptospira interrogans em cães de Belo Horizonte, Minas Gerais, 2001 a 2002. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 58, 167–174.

  • Mascolli, R, Soto, FRM, Bernardi, F, Ito, FH, Pinheiro, SR, Guilloux, AGA, Azevedo, SS, Fernandes, ARF, Keid, LB, Morais, ZM, Souza, GO, Vasconcellos, SA, 2016. Prevalência e fatores de risco para a leptospirose e brucelose na população canina da Estância Turística de Ibiúna, São Paulo, Brasil. Arquivos do Instituto Biológico, 83, 1–7.

  • Morikawa, VM, 2010. Leptospirose. In: Programa de Zoonoses região Sul. Manual de Zoonoses. Curitiba, PR, 2 ed., v. 1, p. 91–99.

  • Musso, D, La Scola, B, 2013. Laboratory diagnosis of leptospirosis: A challenge. Journal of Microbiology, Immunology and Infection, 46, 245–252.

  • Pinotti, BT, Naxara, L, Pardini, R, 2011. Diet and food selection by small mammals in an old-growth Atlantic forest of south-eastern Brazil. Studies on Neotropical Fauna and Environment, 46, 1–9.

  • Queirogas, VL. de., 2010. Capivaras (Rodentia) e carrapatos (Acari: Ixodidae) [manuscrito]: alterações ecológicas e a interação do hospedeiro e parasita em áreas urbanas. 57 p. Dissertação (Mestrado) – Programa de Pós-Graduação em Ecologia e Conservação de Recursos Naturais, Universidade Federal de Uberlândia. Uberlândia.

  • Querino, AMV, Delbem, ACB, Oliveira, RC, Silva, FG, Muller, EE, Freire, RL, Freitas, JC, 2003. Fatores de risco associados à leptospirose em cães do município de Londrina-PR. Semina: Ciências Agrárias, 24, 27–34.

  • Reis, NR, Peracchi, AL, Pedro, WA, Lima, IP, 2006. Mamíferos do Brasil. Londrina, p. 437.

  • Ribeiro, JF, Walter, BMT, 2008. As principais fitofisionomias do bioma Cerrado. In: Sano, SM, Almeida, SP, Ribeiro, JF. Cerrado: Ecologia e flora. Embrapa Informação Tecnológica, Brasília, cap. 6, p. 152–212.

  • Silva, WB, Simões, LB, Padovani, CR, Langoni, H, Lopes, ALS, Modolo, JR, 2009. Inquérito sorológico e distribuição espacial da leptospirose canina em área territorial urbana da cidade de Botucatu, São Paulo. Veterinária e Zootecnia, 16, 655–668.

  • Silva, RC, Costa, VM, Shimabukuro, FH, Richini-Pereira, VB, Menozzi, BD, Langoni, H, 2012. Frequency of Leptospira spp. in sheep from Brazilian slaughterhouses and its association with epidemiological variables. Pesquisa Veterinária Brasileira, 32, 194–198.

  • Silva, FJ, Santos, CEP, Silva, TR, Silva, GCP, Loffler, SG, Brihuega, B, Alarcon, MFF, Curci, VCM, Mathias, LA, 2015. Pesquisa de leptospiras e de anticorpos contra leptospiras em animais e humanos de propriedades rurais nos biomas brasileiros Pantanal e Caatinga. Brazilian Journal of Veterinary Research and Animal Science, 52, 234–248.

  • Vanasco, NB, Sequeira, MD, Sequeira, G, Tarabla, HD, 2003. Associations between leptospiral infection and seropositivity in rodents and environmental characteristics in Argentina. Preventive Veterinary Medicine, 60, 227–235.

  • Vedhagiri, K, Natarajaseenivasan, K, Prabhakaran, SG, Selvin, J, Narayanan, R, Shouche YS, Vijayachari, P, Ratnam, S, 2010. Characterization of Leptospira borgpetersenii isolates from field rats (Rattus norvegicus) by 16S RRNA and LipL32 gene sequences. Brazilian Journal of Microbiology, 41, 150–157.

  • Vinetz, JM, 2001. Leptospirosis. Current Opinion in Infectious Diseases, 527–538.

Download references

Acknowledgements

The authors are thankful to the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) for the financial support and the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).

Author information

Authors and Affiliations

  1. Laboratório de Doenças Infectocontagiosas, Faculdade de Medicina Veterinária of the Universidade Federal de Uberlândia, Rua Ceará, Bloco 2D, Segundo andar, Sala 33, 38.405-315, Uberlândia, State of Minas Gerais, Brazil

    D. O. Gomes, G. B. Ramos, V. B. A. Alves, A. Z. Ciuffa, L. P. Cuccato, T. F. M. dos Reis & A. M. C. Lima

  2. Laboratório de Ixodologia, Faculdade de Medicina Veterinária of the Universidade Federal de Uberlândia, Rua Ceará, Bloco 2D, Segundo andar, Sala 33, 38.405-315, Uberlândia, State of Minas Gerais, Brazil

    M. C. Gonçalves, G. V. Tolesano, V. S. Rodrigues & M. P. J. Szabó

Authors
  1. D. O. Gomes
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. B. Ramos
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. V. B. A. Alves
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. Z. Ciuffa
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. L. P. Cuccato
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. T. F. M. dos Reis
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. A. M. C. Lima
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. M. C. Gonçalves
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. G. V. Tolesano
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. V. S. Rodrigues
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. M. P. J. Szabó
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to D. O. Gomes.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

The Ethics Committee for Animal Utilization of the Universidade Federal de Uberlândia (N. 185/11) previously approved the study. The license for capturing the small mammals was issued by the Instituto Chico Mendes de Conservação da Biodiversidade (ICMBio/SISBIO N. 22629-1).

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Gomes, D.O., Ramos, G.B., Alves, V.B.A. et al. Occurrence of anti-Leptospira spp. antibodies in Rhipidomys spp. from a forest fragment of the Brazilian Cerrado. Trop Anim Health Prod 49, 555–559 (2017). https://doi.org/10.1007/s11250-017-1227-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11250-017-1227-6

Keywords

Search

Navigation