Abstract
Conditions for hydroxyapatite (HAP) synthesis in aqueous solutions by hydrolysis of α-Ca3(PO4)2 were studied. Temperature exerts a substantial effect on the rate of α-Ca3(PO4)2 hydrolysis and also changes the morphology of the reaction products. At 40 °C, the plate-like intersecting (perpendicular to the surface of the initial particles) crystals of HAP grow. Their maximum size after the 24-h hydrolysis is 1–2 µm. Needle like HAP crystals are formed upon boiling of the suspension. The morphology observed for the HAP particles agrees well with the conclusions obtained by analysis of the kinetics of tricalcium phosphate hydrolysis.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
W. Suchanek and M. Yashimura, J. Mater. Res., 1998, 13, 94.
E. Fernandez, F. J. Gil, M. P. Ginebra, F. C. M. Driessens, J. A. Planell, and S. M. Best, J. Mater. Sci.: Materials in Medicine, 1999, 10, 169.
S. V. Dorozhkin and M. Epple, Angew. Chem., Int. Ed., 2002, 41, 3130.
M. Vallet-Regi, J. Chem. Soc., Dalton Trans, 2000, 97.
M. P. Ginebra, E. Fernandez, F. Driessens, and J. A. Planell, J. Am. Ceram. Soc., 1999, 82, 2808.
F. H. Lin, Ch. J. Liao, K. Sh. Chen, J. Sh. Sun, and Ch. P. Lin, Biomaterials, 2001, 22, 2981.
L. Yubao, Zh. Xingdong, and K. De Groot, Biomaterials, 1997, 18, 737.
A. Bigi, E. Boanini, R. Botter, S. Panzaolta, and K. Rubini, Biomaterials, 2002, 23, 1849.
K. S. TenHuisen and P. W. Brown, Biomaterials, 1998, 19, 2209.
C. Durucan and P. W. Brown, J. Mater. Sci.: Materials in Medicine, 2000, 11, 365.
C. Durucan and P. W. Brown, J. Mater. Sci., 2002, 37, 963.
S. Habelitz, L. Pascual, and A. Duran, J. Mater. Sci.: Materials in Medicine, 2002, 36, 4131.
A. Nakahira and K. Sakamoto, J. Am. Ceram. Soc., 1999, 82, 2029.
K. Sakamoto, Sh. Yamaguchi, A. Nakahira, M. Kaneno, M. Okazaki, J. Ichihara, Y. Tsunawaki, and J. C. Elliott, J. Mater. Sci., 2002, 37, 1033.
A. Rodriguez and A. Lebugle, Colloids Surfaces A: Physiochem. Eng. Aspects, 1998, 45, 191.
M. Tamai, T. Isshiki, K. Nishio, A. Nakahira, M. Nakamura, and H. Endoh, J. Mater. Res., 2003, 18, 2633.
K. S. TenHuisen and P. W. Brown, J. Am. Ceram. Soc., 1999, 82, 2813.
Yu. V. Kolen’ko, A. A. Burukhin, B. R. Churagulov, and N. N. Oleynikov, Materials Letters, 2003, 57, 1124.
D. L. Parkhurst, D. C. Thorstenson, and L. N. Plummer, PHREEQE — A Computer Program for Geochemical Calculations: U.S. Geological Survey Water-Resources Investigations Report, 1980, 80–96, 195 p. (Revised and reprinted August, 1990.)
X. Yang and Zh. Wang, J. Mater. Chem., 1998, 8, 2233.
M. E. Brown, D. Dollimore, and A. K. Galwey, Comprehensive Chemical Kinetics. Reactions in the Solid State, Eds C. H. Bamford and C. F. H. Tipper, Elsevier Sci. Publ. Co., 1980, 22.
S. D. Langstaff, M. Sayer, T. J. N. Smith, S. M. Pugh, S. A. M. Hesp, and W. T. Thompson, Biomaterials, 1999, 20, 1727.
Author information
Authors and Affiliations
Additional information
__________
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 78–85, January, 2005.
Rights and permissions
About this article
Cite this article
Sinitsyna, O.V., Veresov, A.G., Kovaleva, E.S. et al. Synthesis of hydroxyapatite by hydrolysis of α-Ca3(PO4)2 . Russ Chem Bull 54, 79–86 (2005). https://doi.org/10.1007/s11172-005-0220-9
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/s11172-005-0220-9