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Cu(NO3)2-catalyzed nitrodecarboxylation of α,β-unsaturated acids: facile synthesis of (E)-nitroolefins under additive-free conditions

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Abstract

An additive-free, facile, efficient, and ecofriendly protocol for synthesis of (E)-nitroolefins via nitrodecarboxylation of α,β-unsaturated acids has been developed. Cu(NO3)2 was used as both nitrating agent and catalyst. Furthermore, the presented methodology offers several advantages such as easily accessible and stable substrates, inexpensive catalyst, high to excellent yield, short reaction time, and simple posttreatment procedure.

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Acknowledgments

The authors gratefully acknowledge the financial support from the National Natural Science Foundation of China (21102003) and Scientific Research Foundation for the Introduction of Talent of Anhui University of Science and Technology.

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Authors and Affiliations

  1. College of Chemical Engineering, Anhui University of Science & Technology, Huainan, 232001, China

    Zai-Gang Luo, Feng Xu, Yu-Yu Fang, Xue-Mei Xu, Cheng-Tao Feng, Zhong Li & Jie He

  2. Guang Zhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China

    Peng Liu

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  1. Zai-Gang Luo
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  2. Feng Xu
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  4. Peng Liu
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  7. Zhong Li
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  8. Jie He
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Correspondence to Zai-Gang Luo or Jie He.

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Luo, ZG., Xu, F., Fang, YY. et al. Cu(NO3)2-catalyzed nitrodecarboxylation of α,β-unsaturated acids: facile synthesis of (E)-nitroolefins under additive-free conditions. Res Chem Intermed 42, 6079–6087 (2016). https://doi.org/10.1007/s11164-016-2446-6

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