Abstract
Polyesters are widely used for biomedical applications such as drug delivery systems and resorbable implants. The degradation kinetic of these biopolymers can be tailored by the introduction of functional groups in their backbone, leading to a modification of their morphology and hydrophilicity. This is usually realized via long multistep reaction pathways. This contribution describes the emergence of one-step procedures for this purpose including enzymatic and Lewis acid catalyzed polycondensation as well as coordinative ring opening polymerization.
References
Albertsson AC, Varma KI (2003) Recent developments in ring opening polymerization of lactones for biomedical applications. Biomacromolecules 4:1466–1486. doi:10.1021/bm034247
Hu J, Gao W, Kulshrestha A, Gross RA (2006) “Sweet polyesters”: lipase-catalyzed condensation-polymerizations of alditols. Macromolecules 39:6789–6792. doi:10.1021/ma0612834
Ikada Y, Tsuji H (2000) Biodegradable polyesters for medical and ecological applications. Macromol Rapid Commun 21:117–132. doi:10.1002/(SICI)1521-3927(20000201)21:3<117::AID-MARC117>3.0.CO;2-X
Kline BJ, Beckman EJ, Russel AJ (1998) One-step biocatalytic synthesis of linear polyesters with pendant hydroxyl groups. J Am Chem Soc 120:9475–9480. doi:10.1021/ja980890
Kumar A, Kulshresta S, Gao W, Gross RA (2003) Versatile route to polyol polyesters by lipase catalysis. Macromolecules 36:8219–8221. doi:10.1021/ma0351827
Marcincinova-Benabdillah K, Boustta M, Coudane J, Vert M (2001) Novel degradable polymers combining d-gluconic acid, a sugar of vegetal origin, with lactic and glycolic acids. Biomacromolecules 2:1279–1284. doi:10.1021/bm015585j
Masato Minami K (2002) Aliphatic polyester, method for manufacturing aliphatic polyester and method for recycling cellulose. US Patent 6,420,513 B2
Place ES, Evans ED, Stevens MM (2009) Complexity in biomaterials for tissue engineering. Nat Mater 8:457–470. doi:10.1038/nmat2441
Takasu A, Shibata Y, Narukawa Y, Hirabayashi T (2007) Chemoselective dehydration polycondensations of dicarboxylic acids and diols having pendant hydroxyl groups using the room temperature polycondensation method. Macromolecules 40:151–153. doi:10.1021/ma06514
Uhlrich KE, Cannizzaro SM, Langer RS, Shakesheff KM (1999) Polymeric systems for controlled drug release. Chem Rev 99:3181–3198. doi:10.1021/cr940351
Uyama H, Inada K, Kobayashi S (2001) Regioselectivity control in lipase-catalyzed polymerization of divinyl sebacate and triols. Macromol Biosci 1:40–44. doi:10.1002/1616-5195(200101)1:1<40::AID-MABI40>3.0.CO;2-T
Weblinks
Marie Curie Fellowship Association, http://mcfa.eu/
Unity of Catalysis and Solid State Chemistry, http://uccs.univ-lille1.fr/
The Biomaterials Federation of the North of France, http://www.biomaterials.com.fr/
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Zinck, P. One-step synthesis of polyesters specialties for biomedical applications. Rev Environ Sci Biotechnol 8, 231–234 (2009). https://doi.org/10.1007/s11157-009-9168-9
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11157-009-9168-9