Abstract
This study investigated the impact of diets containing various levels of avocado (5, 10 and 15%) on gut health in rats fed for six weeks. Avocado-fed rats had significantly higher food intakes while their body weights remained similar to the control diet-fed rats. No significant changes in intestinal bacterial populations (ileum, cecum and colon) were found in rats fed avocado diets compared to the control diet. Ileum and colon tissues of rats fed avocado diets showed significantly higher expression of genes (β-defensin 1, mucin 3 or mucin 4) and a greater number of mucin-producing goblet cells in the colon. The percentage of avocado in the diet had varying effects in altering the biomarkers, whereby diet containing 15% avocado was the more effective diet. This study delivers new knowledge on the role of avocado on gut health in rats.
References
Dreher ML, Davenport AJ (2013) Hass avocado composition and potential health effects. Crit Rev Food Sci Nutr 53:738–750
Simpson HL, Campbell BJ (2015) Review article: dietary fibre–microbiota interactions. Aliment Pharmacol Ther 42:158–179
Conlon M, Bird A (2015) The impact of diet and lifestyle on gut microbiota and human health. Nutrients 7:17
Sivakumaran S, Huffman L, Sivakumaran S (2017) The concise New Zealand food composition tables, 12th edn. The New Zealand Institute for Plant and Food Research Limited and Ministry of Health, Palmerston North
Fava F, Gitau R, Griffin BA, Gibson GR, Tuohy KM, Lovegrove JA (2013) The type and quantity of dietary fat and carbohydrate alter faecal microbiome and short-chain fatty acid excretion in a metabolic syndrome ‘at-risk’ population. Int J Obes 37:216–223
Louis P, Hold GL, Flint HJ (2014) The gut microbiota, bacterial metabolites and colorectal cancer. Nat Rev Microbiol 12:661–672
Bentley-Hewitt K, Blatchford P, Parkar S, Ansell J, Pernthaner A (2012) Digested and fermented green kiwifruit increases human β-defensin 1 and 2 production in vitro. Plant Foods Hum Nutr 67:208–214
Hazlett L, Wu M (2011) Defensins in innate immunity. Cell Tissue Res 343:175–188
Tanabe H, Ito H, Sugiyama K, Kiriyama S, Morita T (2006) Dietary indigestible components exert different regional effects on luminal mucin secretion through their bulk-forming property and fermentability. Biosci Biotechnol Biochem 70:1188–1194
Paturi G, Butts CA, Bentley-Hewitt KL, Ansell J (2014) Influence of green and gold kiwifruit on indices of large bowel function in healthy rats. J Food Sci 79:H1611–H1620
Acknowledgements
We thank Sheridan Martell, Hannah Dinnan, Sue Middlemiss-Kraak, Halina Stoklosinski and Thanuja Herath for their technical assistance. This study was funded by the Ministry of Business, Innovation and Employment (C11X1312), New Zealand.
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Paturi, G., Butts, C.A. & Bentley-Hewitt, K.L. Influence of Dietary Avocado on Gut Health in Rats. Plant Foods Hum Nutr 72, 321–323 (2017). https://doi.org/10.1007/s11130-017-0614-5
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DOI: https://doi.org/10.1007/s11130-017-0614-5