Targeted transport systems for drug delivery to the central nervous system (CNS) are reviewed. A modern classification of dosage forms according to generation and characteristic features is presented. The main targeted delivery systems for CNS drugs based on nanocarriers such as liposomes, polymer nanoparticles, polymer micelles, solid lipid nanoparticles, and nanoparticles of chitosan and human serum albumin are examined.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 53, No. 9, pp. 33 – 39, September, 2019.
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Skorobogatova, A.I., Terent’eva, O.A., Vainshtein, V.A. et al. Targeted Transport as a Promising Method of Drug Delivery to the Central Nervous System (Review). Pharm Chem J 53, 845–851 (2019). https://doi.org/10.1007/s11094-019-02088-8
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DOI: https://doi.org/10.1007/s11094-019-02088-8