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Radiation-induced optic neuritis after pituitary adenoma radiosurgery in a patient with multiple sclerosis: case report

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Abstract

Objective and Importance To describe a rare case of optic neuritis onset after Gamma Knife stereotactic radiosurgery. Clinical Presentation Nine years after transsphenoidal subtotal resection of a pituitary adenoma, this 43-year-old woman had elevated serum prolactin levels and headaches. Intervention Gamma Knife stereotactic radiosurgery to residual pituitary tumor. Conclusion To our knowledge, this is the first report of radiation-induced optic neuritis after radiosurgery in a patient with multiple sclerosis.

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Abbreviations

ATM:

Ataxia telangiectasia-mutated protein

CNS:

Central nervous system

CSF:

Cerebrospinal fluid

MRI:

Magnetic resonance imaging

MS:

Multiple sclerosis

PRL:

Prolactin

SRS:

Stereotactic radiosurgery

TN:

Trigeminal neuralgia

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Authors and Affiliations

  1. Department of Radiation Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA

    Thomas B. Daniels, Bruce E. Pollock, Robert C. Miller & Paul D. Brown

  2. Department of Neurologic Surgery, Mayo Clinic, Rochester, MN, USA

    Bruce E. Pollock

  3. Department of Neurology, Mayo Clinic, Rochester, MN, USA

    Claudia F. Lucchinetti

  4. Department of Ophthalmology, Mayo Clinic, Rochester, MN, USA

    Jacqueline A. Leavitt

Authors
  1. Thomas B. Daniels
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  2. Bruce E. Pollock
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  3. Robert C. Miller
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  4. Claudia F. Lucchinetti
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  5. Jacqueline A. Leavitt
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  6. Paul D. Brown
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Corresponding author

Correspondence to Paul D. Brown.

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Daniels, T.B., Pollock, B.E., Miller, R.C. et al. Radiation-induced optic neuritis after pituitary adenoma radiosurgery in a patient with multiple sclerosis: case report. J Neurooncol 93, 263–267 (2009). https://doi.org/10.1007/s11060-008-9766-3

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  • DOI: https://doi.org/10.1007/s11060-008-9766-3

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