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TiO2 nanoparticles supported on the Fe3O4@SiO2 nanocomposites: a novel magnetic nanocatalyst for the synthesis of 2-aminothiazoles

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Abstract

Nano TiO2 supported on the Fe3O4@SiO2 nanocomposites is introduced as a novel catalyst for the environmental synthesis of 2-aminothiazoles in PEG-200 as a green medium at room temperature. In this reaction, thiourea and N-bromosuccinimide were reacted with various ketones affording the desired 2-aminothiazole compounds. This green protocol has promising features for the reaction response such as simple procedure, high yields, and the ease of separation of pure product, short reaction time, and convenient manipulation. This catalyst was easily separated by an external magnet, and the recovered catalyst was reused several times without any significant loss of activity.

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Acknowledgments

We gratefully acknowledge the financial support from the Research Council of the University of Kashan for supporting this work by Grant No. (256722/III).

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Authors and Affiliations

  1. Laboratory of Organic Compound Research, Department of Organic Chemistry, College of Chemistry, University of Kashan, P.O. Box: 87317-51167, Kashan, Iran

    Javad Safari, Zahra Abedi-Jazini, Zohre Zarnegar & Masoud Sadeghi

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  1. Javad Safari
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  2. Zahra Abedi-Jazini
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  3. Zohre Zarnegar
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  4. Masoud Sadeghi
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Correspondence to Zohre Zarnegar.

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Safari, J., Abedi-Jazini, Z., Zarnegar, Z. et al. TiO2 nanoparticles supported on the Fe3O4@SiO2 nanocomposites: a novel magnetic nanocatalyst for the synthesis of 2-aminothiazoles. J Nanopart Res 17, 495 (2015). https://doi.org/10.1007/s11051-015-3298-5

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  • DOI: https://doi.org/10.1007/s11051-015-3298-5

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