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A snapshot on introspection of autism spectrum disorder

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Abstract

Autism spectrum disorder is a neurodevelopmental condition marked by restricted interests and difficulty with social communication. ASD is characterized by heightened neuroinflammation and irregular neuronal connections. ASD is more frequent in male than female with male–female ratio of around 4:1. ASD affects 2.8% or 1 in 36 8-year-olds, based on the CDC’s Morbidity and Mortality Weekly Report. Various factors like Environmental, Genetic, Epigenetic and Developmental factors are linked with genesis of ASD. Repetitive behaviors, Impaired communication skills, difficulty with social interaction are some of the clinical features of ASD. Current Pharmacotherapy of ASD limits to management of symptoms only, not cure. The stem cell therapy has a promising potential to be a breakthrough in treating ASD. Various types of stem cells have been successfully tested in children with ASD. AI has a potential to emerge as a tool for early detection of ASD. Robotics can assist the children with ASD to overcome the challenges associated with ASD.

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Data availability

The datasets generated during and/or analyzed during the current study are available from the corresponding author upon reasonable request.

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Funding

We appreciate the support provided by Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research at Pimpri, Pune, 411018 Maharashtra, India for providing the necessary help to conduct this review.

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  1. Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune, 411018, Maharashtra, India

    Govind Kale, Veeranjaneyulu Addepalli & Sharvari Joshi

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  1. Govind Kale
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Contributions

Conceptualization: A.V. Methodology: G.K., Literature search: G.K., A.V., Data analysis: G.K. Writing- original draft preparation: G.K, A.V, S.J Writing-review and editing: G.K, A.V,S.J Supervision: A.V

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Correspondence to Veeranjaneyulu Addepalli.

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Kale, G., Addepalli, V. & Joshi, S. A snapshot on introspection of autism spectrum disorder. Mol Biol Rep 51, 610 (2024). https://doi.org/10.1007/s11033-024-09514-5

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