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Self-assembly nucleic acid-based biopolymers: learn from the nature

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Abstract

This review highlights the recent developments in nucleic acid-based based materials for biomedical applications and functional devices. DNA and RNA are anionic macromolecules composing sugar-phosphate backbone, which usually structure as rod-like double helix with base pair stacking. Electrostatic interactions are the main components in the complex formed between anionic nucleic acid and cationic molecule. These nucleic acid-based biopolymers have significant potential as functional materials for drug delivery, biosensors, and a scaffold for many biodegradable materials.

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Acknowledgements

This work is supported by Kasetsart University Research and Development Institute (KURDI), Kasetsart University, Thailand. The authors would like to gratefully acknowledge Professor Matthew Tirrell from University of Chicago for all the supports.

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Authors and Affiliations

  1. Specialized Center of Rubber and Polymer Materials for Agriculture and Industry (RPM), Department of Materials Science, Faculty of Science, Kasetsart University, Bangkok, Thailand

    Pitchaya Pakornpadungsit & Wirasak Smitthipong

  2. Office of Natural Rubber Research Program, The Thailand Research Fund (TRF), Bangkok, Thailand

    Wirasak Smitthipong

  3. Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90363, Lodz, Poland

    Arkadiusz Chworos

Authors
  1. Pitchaya Pakornpadungsit
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  2. Wirasak Smitthipong
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  3. Arkadiusz Chworos
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Correspondence to Wirasak Smitthipong.

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Pakornpadungsit, P., Smitthipong, W. & Chworos, A. Self-assembly nucleic acid-based biopolymers: learn from the nature. J Polym Res 25, 45 (2018). https://doi.org/10.1007/s10965-018-1441-6

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  • DOI: https://doi.org/10.1007/s10965-018-1441-6

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