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An analytical approach to solutions of master equations for stochastic nonlinear reactions

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Abstract

In this paper we consider a class of nonlinear reactions which are important in stochastic reaction networks. We find the exact solution of the chemical master equation for a class of irreversible and reversible nonlinear reactions. We also present the explicit form of the equilibrium probability solution of the reactions. The results can be used for analyzing stochastic dynamics of important reactions such as binding/unbinding reaction and protein dimerization.

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References

  1. Gillespie D.T.: A rigorous derivation of the chemical master equation. Physica A 188, 404–425 (1992)

    Article  CAS  Google Scholar 

  2. McQuarrie D.A.: Stochastic approach to chemical kinetics. J. Appl. Probab. 4, 413–478 (1967)

    Article  Google Scholar 

  3. Laurenzi I.J.: An analytical solution of the stochastic master equation for reversible bimolecular reaction kinetics. J. Chem. Phys. 113, 3315 (2000)

    Article  CAS  Google Scholar 

  4. Wolkenhauer O., Ullah M., Kolch W., Cho K.-H.: Modelling and simulation of intra cellular dynamics: choosing an appropriate framework. IEEE Trans. NanoBioSci. 3(3), 200–207 (2004)

    Article  Google Scholar 

  5. Horn R.A., Johnson C.R.: Matrix Analysis. Cambridge University Press, Cambridge (1985)

    Google Scholar 

  6. El-Mikkawy M.E.A.: Explicit inverse of a generalized Vandermonde matrix. Appl. Math. Comput. 146, 643–651 (2003)

    Article  Google Scholar 

  7. Krishnakumar A.S., Morf Martin: Eigenvalues of a symmetric tridiagonal matrix: a divide-and-conquer approach. Numerische Mathematik 48, 349–368 (1986)

    Article  Google Scholar 

  8. Lee C.H., Kim K., Kim P.: A moment closure method for stochastic reaction networks. J. Chem. Phys. 130, 134107 (2009)

    Article  Google Scholar 

  9. Kato T.: Perturbation Theory for Linear Operators. Springer, Berlin (1976)

    Book  Google Scholar 

  10. Gadgil C., Lee C.H., Othmer H.G.: A stochastic analysis of first-order reaction networks. Bull. Math. Biol. 67, 901–946 (2005)

    Article  CAS  Google Scholar 

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Correspondence to Chang Hyeong Lee.

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Lee, C.H., Kim, P. An analytical approach to solutions of master equations for stochastic nonlinear reactions. J Math Chem 50, 1550–1569 (2012). https://doi.org/10.1007/s10910-012-9988-7

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  • DOI: https://doi.org/10.1007/s10910-012-9988-7

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