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Latent Tuberculosis Infection Diagnosis Using QuantiFERON-TB Gold Plus Kit Among Correctional Workers: A Cross-Sectional Study in Francisco Beltrão-PR, Brazil

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Abstract

Correctional workers form a high-priority group for tuberculosis control measures because of their high exposure and risk. This cross-sectional study conducted in April and May 2022 included 71 criminal police officers from the State Penitentiary of Francisco Beltrão-PR, Brazil. Their sociodemographic and laboratory data were collected. Latent tuberculosis infection (LTBI) was assessed using a QuantiFERON-TB Gold Plus in-tube test kit. Binary logistic regression was applied to calculate the odds ratios (ORs) and 95% confidence intervals (CI) of the LTBI predictors. The prevalence of LTBI was 22.6% (95% CI, 12.8–32.2%). Factors associated with LTBI were age > 43 years (OR, 0.18; 95% CI, 0.04–0.70; p < 0.014) and the use of medications (OR, 5.13; 95% CI, 1.40–18.87; p < 0.014). The prevalence was close to that estimated worldwide for LTBI in correctional workers, reinforcing the need for occupational health control measures consisting of regular screening and treatment of positive cases of latent infection among correctional workers to reduce the risk of illness and spread of infection in the penitentiary system and community.

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Data Availability

The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Acknowledgements

To the Araucária Foundation of the State of Paraná (ARAUCÁRIA) for the financial assistance (Term of Agreement nº 289/2022).

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Authors and Affiliations

  1. Health Sciences Center, Postgraduate Program in Applied Health Sciences, Western Paraná State University (UNIOESTE), Francisco Beltrão, Brazil

    Maico Trevisol

  2. Health Sciences Center, Faculty of Medicine, Public Health Lab and Biosciences and Health Lab, Western Paraná State University (UNIOESTE), Francisco Beltrão, Brazil

    Thiago Poss Moreira & Gustavo Henrique Baraca Sanvezzo

  3. Faculty of Medicine, Western Paraná State University (UNIOESTE), Cascavel, Brazil

    Sthefanny Josephine Klein Ottoni Guedes

  4. Faculty of Health Sciences, Universidad Autónoma de Chile, Providencia, Chile

    Danilo Rodrigues Pereira da Silva

  5. Health Sciences Center, Postgraduate Program in Applied Health Sciences, Public Health Lab and Biosciences and Health Lab, Western Paraná State University (UNIOESTE), Francisco Beltrão, Brazil

    Guilherme Welter Wendt & Lirane Elize Defante Ferreto

  6. Department of Pharmacy, University of São Paulo, Ribeirão Preto, Brazil

    Harnoldo Colares Coelho

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Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by Maico Trevisol, Thiago Poss Moreira, Gustavo Henrique Baraca Sanvezzo and Lirane Elize Defante Ferreto. The first draft of the manuscript was written by Maico Trevisol and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Lirane Elize Defante Ferreto.

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The authors have no competing interests to declare that are relevant to the content of this article.

Ethical Approval

The study was approved by the Institutional Review Board at the Western Paraná State University [opinion number. 5.346.101]. All participants provided their informed consent to participate in the study.

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Trevisol, M., Moreira, T.P., Sanvezzo, G.H.B. et al. Latent Tuberculosis Infection Diagnosis Using QuantiFERON-TB Gold Plus Kit Among Correctional Workers: A Cross-Sectional Study in Francisco Beltrão-PR, Brazil. J Community Health 48, 600–605 (2023). https://doi.org/10.1007/s10900-023-01201-z

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