Abstract
The purpose of this study was to investigate the effect of fiber orientation of a fiber-reinforced composite (FRC) made of poly-methyl-methacrylate (PMMA) and E-glass to the surface fabrication process by solvent dissolution. Intention of the dissolution process was to expose the fibers and create a macroporous surface onto the FRC to enhance bone bonding of the material. The effect of dissolution and fiber direction to the bone bonding capability of the FRC material was also tested. Three groups of FRC specimens (n = 18/group) were made of PMMA and E-glass fiber reinforcement: (a) group with continuous fibers parallel to the surface of the specimen, (b) continuous fibers oriented perpendicularly to the surface, (c) randomly oriented short (discontinuous) fibers. Fourth specimen group (n = 18) made of plain PMMA served as controls. The specimens were subjected to a solvent treatment by tetrahydrofuran (THF) of either 5, 15 or 30 min of time (n = 6/time point), and the advancement of the dissolution (front) was measured. The solvent treatment also exposed the fibers and created a surface roughness on to the specimens. The solvent treated specimens were embedded into plaster of Paris to simulate bone bonding by mechanical locking and a pull-out test was undertaken to determine the strength of the attachment. All the FRC specimens dissolved as function of time, as the control group showed no marked dissolution during the study period. The specimens with fibers along the direction of long axis of specimen began to dissolve significantly faster than specimens in other groups, but the test specimens with randomly oriented short fibers showed the greatest depth of dissolution after 30 min. The pull-out test showed that the PMMA specimens with fibers were retained better by the plaster of Paris than specimens without fibers. However, direction of the fibers considerably influenced the force of attachment. The fiber reinforcement increases significantly the dissolution speed, and the orientation of the glass fibers has great effect on the dissolving depth of the polymer matrix of the composite, and thus on the exposure of fibers. The glass fibers exposed by the solvent treatment enhanced effectively the attachment of the specimen to the bone modeling material.
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References
Kaufmann TJ, Jensen ME, Ford G, et al. Cardiovascular effects of polymethylmethacrylate use in percutaneous vertebroplasty. Am J Neuroradiol. 2002;23(4):601–4.
Lieberman IH, Togawa D, Kayanja MM. Vertebroplasty and kyphoplasty: filler materials. Spine J. 2005;5(6, Supplement):S305–16.
Gomaa A, Lee RM, Liu CS. Polypseudophakia for cataract surgery: 10-year follow-up on safety and stability of two poly-methyl-methacrylate (PMMA) intraocular lenses within the capsular bag. Eye (Lond). 2011;25(8):1090–3.
Becker LC, Bergfeld WF, Belsito DV, et al. Final report of the cosmetic ingredient review expert panel safety assessment of polymethyl methacrylate (PMMA), methyl methacrylate crosspolymer, and methyl methacrylate/glycol dimethacrylate crosspolymer. Int J Toxicol. 2011;30(3 Suppl):54S–65S.
Väkiparta M, Yli-urpo A, Vallittu PK. Flexural properties of glass fiber reinforced composite with multiphase biopolymer matrix. J Mater Sci Mater Med. 2004;15(1):7–11.
Mattila RH, Lassila LVJ, Vallittu PK. Production and structural characterisation of porous fibre-reinforced composite. Compos A Appl Sci Manuf. 2004;35(6):631–6.
Dyer SR, Lassila LV, Jokinen M, et al. Effect of cross-sectional design on the modulus of elasticity and toughness of fiber-reinforced composite materials. J Prosthet Dent. 2005;94(3):219–26.
Zhao DS, Moritz N, Laurila P, et al. Development of a multi-component fiber-reinforced composite implant for load-sharing conditions. Med Eng Phys. 2009;31(4):461–9.
Chan C-M, Ko T-M, Hiraoka H. Polymer surface modification by plasmas and photons. Surf Sci Rep. 1996;24(1–2):1–54.
Chen J, Zhuang H, Zhao J, et al. Solvent effects on polymer surface structure. Surf Interface Anal. 2001;31(8):713–20.
Goddard JM, Hotchkiss JH. Polymer surface modification for the attachment of bioactive compounds. Prog Polym Sci. 2007;32(7):698–725.
Chu PK, Chen JY, Wang LP, et al. Plasma-surface modification of biomaterials. Mater Sci Eng R Rep. 2002;36(5–6):143–206.
Mendonça G, Mendonça DBS, Aragão FJL, et al. Advancing dental implant surface technology—from micron–to nanotopography. Biomaterials. 2008;29(28):3822–35.
Mattila RH. Fibre-reinforced composite implant: in vitro mechanical interlocking with bone model material and residual monomer analysis. J Mater Sci. 2006;41(13):4321.
Puska MA, Narhi TO, Aho AJ, et al. Flexural properties of crosslinked and oligomer-modified glass-fibre reinforced acrylic bone cement. J Mater Sci Mater Med. 2004;15(9):1037–43.
Puska MA, Lassila LV, Närhi TO, et al. Improvement of mechanical properties of oligomer-modified acrylic bone cement with glass-fibers. Appl Compos Mater. 2004;11(1):17–31.
Hautamäki MP, Aho AJ, Alander P, et al. Repair of bone segment defects with surface porous fiber-reinforced polymethyl methacrylate (PMMA) composite prosthesis: histomorphometric incorporation model and characterization by SEM. Acta Orthop. 2008;79(4):555–64.
Aho AJ, Hautamäki M, Mattila R, et al. Surface porous fibre-reinforced composite bulk bone substitute. Cell Tissue Banking. 2004;5(4):213–21.
Mattila RH, Laurila P, Rekola J, et al. Bone attachment to glass-fibre-reinforced composite implant with porous surface. Acta Biomater. 2009;5(5):1639–46.
Vallittu PK. Curing of a silane coupling agent and its effect on the transverse strength of autopolymerizing polymethylmethacrylate-glass fibre composite. J Oral Rehabil. 1997;24(2):124–30.
Nganga S, Ylä-Soininmäki A, Lassila LVJ, et al. Interface shear strength and fracture behaviour of porous glass-fibre-reinforced composite implant and bone model material. J Mech Behav Biomed Mater. 2011;4(8):1797–804.
Ballo AM, Lassila LV, Vallittu PK, et al. Load bearing capacity of bone anchored fiber-reinforced composite device. J Mater Sci Mater Med. 2007;18(10):2025–31.
Horowitz S, Doty S, Lane J, et al. Studies of the mechanism by which the mechanical failure of polymethylmethacrylate leads to bone resorption. J Bone Joint Surg Am. 1993;75(6):802–13.
Vallittu PK. Peak temperatures of some prosthetic acrylates on polymerization. J Oral Rehabil. 1996;23(11):776–81.
Revell PA, Braden M, Freeman MAR. Review of the biological response to a novel bone cement containing poly(ethyl methacrylate) and n-butyl methacrylate. Biomaterials. 1998;19(17):1579–86.
Lu JX, Huang ZW, Tropiano P, et al. Human biological reactions at the interface between bone tissue and polymethylmethacrylate cement. J Mater Sci Mater Med. 2002;13(8):803–9.
Bruens ML, Pieterman H, de Wijn JR, et al. Porous polymethylmethacrylate as bone substitute in the craniofacial area. J Craniofac Surg. 2003;14(1):63–8.
Vallittu PK, Miettinen V, Alakuijala P. Residual monomer content and its release into water from denture base materials. Dent Mater. 1995;11(6):338–42.
Vallittu PK, Ruyter IE, Buykuilmaz S. Effect of polymerization temperature and time on the residual monomer content of denture base polymers. Eur J Oral Sci. 1998;106(1):588–93.
Frazer RQ, Byron RT, Osborne PB, West KP. PMMA: an essential material in medicine and dentistry. J Long Term Eff Med Implant. 2005;15(6):629–39.
Narva KK, Lassila LV, Vallittu PK. The static strength and modulus of fiber reinforced denture base polymer. Dent Mater Off Publ Acad Dent Mater. 2005;21(5):421–8.
Vallittu PK. Impregnation of glass fibres with polymethylmethacrylate using a powder-coating method. Appl Compos Mater. 1995;2(1):51–8.
Vallittu PK. Flexural properties of acrylic resin polymers reinforced with unidirectional and woven glass fibers. J Prosthet Dent. 1999;81(3):318–26.
Miller-Chou BA, Koenig JL. A review of polymer dissolution. Prog Polym Sci. 2003;28(8):1223–70.
Ueberreiter K, Asmussen F. Velocity of dissolution of polymers. Part I. J Polym Sci. 1962;57(165):187–98.
Hildebrand J, Scott RL. The solubility of nonelectrolytes. 3rd ed. New York: Reinhold; 1950.
Hansen CM. 50 Years with solubility parameters—past and future. Prog Org Coat. 2004;51(1):77–84.
Belmares M, Blanco M, Goddard WA, et al. Hildebrand and Hansen solubility parameters from molecular dynamics with applications to electronic nose polymer sensors. J Comput Chem. 2004;25(15):1814–26.
Ribar T, Bhargava R, Koenig JL. FT-IR imaging of polymer dissolution by solvent mixtures. 1. Solvents. Macromolecules. 2000;33(23):8842–9.
Stamatialis DF, Sanopoulou M, Raptis I. Swelling and dissolution behavior of poly(methyl methacrylate) films in methyl ethyl ketone/methyl alcohol mixtures studied by optical techniques. J Appl Polym Sci. 2002;83(13):2823–34.
Burnside SD, Giannelis EP. Synthesis and properties of new poly(dimethylsiloxane) nanocomposites. Chem Mater. 1995;7(9):1597–600.
Thomason JL, Porteus G. Swelling of glass-fiber reinforced polyamide 66 during conditioning in water, ethylene glycol, and antifreeze mixture. Polym Compos. 2011;32(4):639–47.
Park S, Jin J. Effect of silane coupling agent on interphase and performance of glass fibers/unsaturated polyester composites. J Colloid Interface Sci. 2001;242(1):174–9.
Debnath S, Wunder SL, McCool JI, et al. Silane treatment effects on glass/resin interfacial shear strengths. Dent Mater. 2003;19(5):441–8.
Shim V, Boheme J, Josten C, et al. Use of Polyurethane Foam in Orthopaedic Biomechanical Experimentation and Simulation. In Zafar F, Sharmin E, eds.Polyurethane. 1st ed.: InTech 2012:171–200.
ASTM International. Standard Specification for Rigid Polyurethane Foam for Use as a Standard Material for Testing Orthopaedic Devices and Instruments. 2012;F1839 - 08(2012).
Acknowledgments
We thank laboratory technicians Hanna Mark and Päivi Mäki for preparation of the specimens. The study was funded by the University of Turku Foundation, Allan Aho Fund and Orion-Farmos Research Foundation. The study belongs to the activity of BioCity Turku Biomaterials Research Program (www.biomaterials.utu.fi).
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Hautamäki, M.P., Puska, M., Aho, A.J. et al. Surface modification of fiber reinforced polymer composites and their attachment to bone simulating material. J Mater Sci: Mater Med 24, 1145–1152 (2013). https://doi.org/10.1007/s10856-013-4890-9
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DOI: https://doi.org/10.1007/s10856-013-4890-9