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Epitaxial growth of the zinc oxide nanorods, their characterization and in vitro biocompatibility studies

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Abstract

Here, we have synthesized Zinc Oxide (ZnO) nanorods at room temperature using zinc acetate and hexamethylenetetramine as precursors followed by characterization using X-ray diffraction (XRD), fourier transform infra red spectroscopy, scanning electron microscopy (SEM) and transmission electron microscopy. The growth of the synthesized ZnO was found to be very close to its hexagonal nature, which is confirmed by XRD. The nanorods were grown perpendicular to the long-axis and grew along the [001] direction, which is the nature of ZnO growth. The morphology of the synthesized ZnO nanorods was also confirmed by SEM. The size of the nanorod was estimated to be around 20–25 nm in diameter and approximately 50–60 nm in length. Our biocompatibility studies using synthesized ZnO showed no significant dose- or time-dependent increase in the formation of free radicals, accumulation of peroxidative products, antioxidant depletion or loss of cell viability on lung epithelial cells.

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Acknowledgments

This work was supported by NASA funding NNX08BA47A: NCC-1-02038: NIH-1P20MD001822-1: NASA NSTI. This work was also supported by the NSF CREST.

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Authors and Affiliations

  1. Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA, 23504, USA

    Ramya Gopikrishnan, Kai Zhang, Prabakaran Ravichandran, Santhoshkumar Biradar, Vani Ramesh, Virupaxi Goornavar, Robert B. Jeffers, Aswini Pradhan, Joseph C. Hall & Govindarajan T. Ramesh

  2. Department of Biotechnology, Pondicherry University, Pondicherry, 605014, India

    Sudhakar Baluchamy

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  1. Ramya Gopikrishnan
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  2. Kai Zhang
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Correspondence to Govindarajan T. Ramesh.

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Gopikrishnan, R., Zhang, K., Ravichandran, P. et al. Epitaxial growth of the zinc oxide nanorods, their characterization and in vitro biocompatibility studies. J Mater Sci: Mater Med 22, 2301 (2011). https://doi.org/10.1007/s10856-011-4405-5

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  • DOI: https://doi.org/10.1007/s10856-011-4405-5

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