Abstract
The current feasibility study examined the adherence, reliability, and assessment potential of an evidence-based game-like mobile Monitoring Tool (Akili Interactive Labs), to monitor 100 participants’ cognition for eight sessions at a summer camp for children with special needs. A validated measure of attention was administered at baseline. In the last session, participants completed an exit questionnaire. The Monitoring Tool was found to be enjoyable, and showed a high rate of adherence. No Monitor-related adverse events were reported. Monitor metrics showed good reliability across repeated measurements, indicating it is stable over long-term cognitive monitoring. There was evidence that the Monitoring Tool was able to detect differences in cognition between the children diagnosed with attention deficit hyperactivity disorder and autism spectrum disorders.



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Acknowledgments
We would like to recognize the children, staff and leadership at Ramapo for Children for their participation. We would especially like to recognize the research assistants who conducted the study Laurel Kiyabu Morgan, Juliana Demicco, Gabi Verdoni, Adriana Gonzalez, Beatrice Baker, Angela Law, Dottie Bradshaw, Reeti Pal, Brianna Morales, and Gabbi Gaddy. In addition, we would like to thank Dr. Mary McKay for her mentorship on this project. This work was presented as a poster in October 2017 at the annual meeting for the American Academy of Child & Adolescent Psychiatry, Washington, D.C.
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RF conceived of the study, planned its design, coordinated data collection, participated in data interpretation, and drafted the manuscript; NC participated in the study design, coordinated data collection and helped draft the manuscript; JB planned the study design, performed the statistical analysis, and participated in data interpretation; JZ performed the statistical analysis. All authors read, edited and approved the final manuscript.
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Rachel Flynn and Nirmaliz Colón-Acosta both were employees of Ramapo for Children, the data collection site, at various points of time. Jeffrey Bower is an employee of Akili Interactive whose product was used. In addition, Jimmy Zhou was an employee of Akili Interactive.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
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Flynn, R.M., Colón-Acosta, N., Zhou, J. et al. A Game-Based Repeated Assessment for Cognitive Monitoring: Initial Usability and Adherence Study in a Summer Camp Setting. J Autism Dev Disord 49, 2003–2014 (2019). https://doi.org/10.1007/s10803-019-03881-w
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DOI: https://doi.org/10.1007/s10803-019-03881-w