Skip to main content
Log in

Diagnosis of retinal damage using Resnet rescaling and support vector machine (Resnet-RS-SVM): a case study from an Indian hospital

  • Original Paper
  • Published:
International Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

This study aims to address the challenge of identifying retinal damage in medical applications through a computer-aided diagnosis (CAD) approach. Data was collected from four prominent eye hospitals in India for analysis and model development.

Methods

Data was collected from Silchar Medical College and Hospital (SMCH), Aravind Eye Hospital (Tamil Nadu), LV Prasad Eye Hospital (Hyderabad), and Medanta (Gurugram). A modified version of the ResNet-101 architecture, named ResNet-RS, was utilized for retinal damage identification. In this modified architecture, the last layer's softmax function was replaced with a support vector machine (SVM). The resulting model, termed ResNet-RS-SVM, was trained and evaluated on each hospital's dataset individually and collectively.

Results

The proposed ResNet-RS-SVM model achieved high accuracies across the datasets from the different hospitals: 99.17% for Aravind, 98.53% for LV Prasad, 98.33% for Medanta, and 100% for SMCH. When considering all hospitals collectively, the model attained an accuracy of 97.19%.

Conclusion

The findings demonstrate the effectiveness of the ResNet-RS-SVM model in accurately identifying retinal damage in diverse datasets collected from multiple eye hospitals in India. This approach presents a promising advancement in computer-aided diagnosis for improving the detection and management of retinal diseases.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

Data availability

The datasets generated during and/or analyzed during the current study are available in the IEEE data port. https://ieee-dataport.org/documents/retinal-detachment-dataset

Code availability

The code generated and/or analyzed during the current study is available from the corresponding author upon reasonable request.

References

  1. Oh EH, Imanaka Y, Evans E (2005) Determinants of the diffusion of computed tomography and magnetic resonance imaging. Int J Technol Assess Health Care 21(1):73–80

    Article  PubMed  Google Scholar 

  2. Lazaro P, Fitch K (1995) The distribution of “big ticket” medical technologies in OECD countries. Int J Technol Assess Health Care 11(3):552–570

    Article  CAS  PubMed  Google Scholar 

  3. Pennington KL, Deangelis MM (2016) Epidemiology of age-related macular degeneration (AMD): associations with cardiovascular disease phenotypes and lipid factors. Eye Vis 3:34

    Article  Google Scholar 

  4. Boyer DS, Hopkins JJ, Sorof J, Ehrlich JS (2013) Anti-vascular endothelial growth factor therapy for diabetic macular edema. Ther Adv Endocrinol Metab 4(6):151–169. https://doi.org/10.1177/2042018813512360.PMID:24324855;PMCID:PMC3855829

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Schmidt-Erfurth U, Sadeghipour A, Gerendas BS, Waldstein SM, Bogunović H (2018) Artificial intelligence in retina. Prog Retinal Eye Res 67:1–29

    Article  Google Scholar 

  6. Mehta H, Tufail A, Daien V, Lee AY, Nguyen V, Ozturk M, Gillies MC (2018) Real-world outcomes in patients with neovascular age-related macular degeneration treated with intravitreal vascular endothelial growth factor inhibitors. Prog Retinal Eye Res 65:127–146

    Article  CAS  Google Scholar 

  7. Boyer DS, Schmidt-Erfurth U, van LookerenCampagne M, Henry EC, Brittain C (2017) The pathophysiology of geographic atrophy secondary to age-related macular degeneration and the complement pathway as a therapeutic target. Retina 37(5):819

    Article  PubMed  PubMed Central  Google Scholar 

  8. Tang MCS, Teoh SS, Ibrahim H (2022) Retinal vessel segmentation from fundus images using DeepLabv3+. In: 2022 IEEE 18th international colloquium on signal processing & applications (CSPA), pp. 377–381

  9. Tang MCS, Teoh SS, Ibrahim H, Embong Z (2022) A deep learning approach for the detection of neovascularization in fundus images using transfer learning. IEEE Access 10:20247–20258. https://doi.org/10.1109/ACCESS.2022.3151644

    Article  Google Scholar 

  10. Tang MCS, Teoh SS (2020) Blood vessel segmentation in fundus images using Hessian matrix for diabetic retinopathy detection. In: 2020 11th IEEE annual information technology, electronics and mobile communication conference (IEMCON), pp. 0728–0733

  11. Tang MCS, Teoh SS, Ibrahim H, Embong Z (2021) Neovascularization detection and localization in fundus images using deep learning. Sensors 21(16):5327. https://doi.org/10.3390/s21165327

    Article  PubMed  PubMed Central  Google Scholar 

  12. Obermeyer Z, Emanuel EJ (2016) Predicting the future—big data, machine learning, and clinical medicine. N Engl J Med 375(13):1216

    Article  PubMed  PubMed Central  Google Scholar 

  13. Athanasopoulou K, Daneva GN, Adamopoulos PG, Scorilas A (2022) Artificial intelligence: the milestone in modern biomedical research. Bioinformatics 2(4):727–744. https://doi.org/10.3390/biomedinformatics2040049

    Article  Google Scholar 

  14. Alzubaidi L, Zhang J, Humaidi AJ et al (2021) Review of deep learning: concepts, CNN architectures, challenges, applications, future directions. J Big Data 8:53. https://doi.org/10.1186/s40537-021-00444-8

    Article  PubMed  PubMed Central  Google Scholar 

  15. Sethy PK, Behera SK (2021) A data constrained approach for brain tumour detection using fused deep features and SVM. Multimedia Tools Appl 80:28745–28760. https://doi.org/10.1007/s11042-021-11098-2

    Article  Google Scholar 

  16. Sethy PK, Barpanda NK, Rath AK, Behera SK (2020) Nitrogen deficiency prediction of rice crop based on convolutional neural network. J Ambient Intell Humaniz Comput. https://doi.org/10.1007/s12652-020-01938-8

    Article  Google Scholar 

  17. Dash S, Sethy PK, Behera SK (2023) Cervical transformation zone segmentation and classification based on improved inception-resnet-V2 using colposcopy images. Cancer Inform. https://doi.org/10.1177/11769351231161477

    Article  PubMed  PubMed Central  Google Scholar 

  18. Sethy PK, Barpanda NK, Rath AK, Behera SK (2020) Rice false smut detection based on faster R-CNN. Indones J Electr Eng Comput Sci. https://doi.org/10.11591/ijeecs.v19.i3.pp%25p

    Article  Google Scholar 

  19. Behera SK, Rath AK, Sethy PK (2021) Fruits yield estimation using faster R-CNN with MIoU. Multimed Tools Appl 80:19043–19056. https://doi.org/10.1007/s11042-021-10704-7

    Article  Google Scholar 

  20. Yamashita R, Nishio M, Do RKG et al (2018) Convolutional neural networks: an overview and application in radiology. Insights Imaging 9:611–629. https://doi.org/10.1007/s13244-018-0639-9

    Article  PubMed  PubMed Central  Google Scholar 

  21. Szegedy C, Ioffe S, Vanhoucke V, Alemi AA (2017) Inception-v4, inception-resnet, and the impact of residual connections on learning. AAAI 4:12

    Google Scholar 

  22. He K, Zhang X, Ren S, Sun J (2016) Deep residual learning for image recognition. In: proceedings of the 2016 IEEE conference on computer vision and pattern recognition (CVPR), Las Vegas, NV, U.S.A., 27–30 June 2016, pp. 770–778

  23. Huang G, Liu S, Maaten L, et al. (2018) Condensenet: an efficient densenet using learned group convolutions. In: conference on computer vision and pattern recognition, pp. 2752–2761

  24. Brachmann E, Rother C (2021) Visual camera re-localization from RGB and RGB-D images using DSAC. IEEE Trans Pattern Anal Mach Intell 44:5847–5865

    Google Scholar 

  25. Shafiq M, Gu Z (2022) Deep residual learning for image recognition: a survey. Appl Sci 12(18):8972. https://doi.org/10.3390/app12188972

    Article  CAS  Google Scholar 

  26. Tang MCS, Teoh SS (2023) Brain tumor detection from MRI images based on ResNet18. In: 2023 6th international conference on information systems and computer networks (ISCON), pp. 1–5

  27. Zhang L, Schaeffer H (2020) Forward stability of ResNet and its variants. J Math Imaging Vision 62:328–351

    Article  Google Scholar 

  28. Hu J, Shen L, Sun G (2018) Squeeze-and-excitation networks. In: Proceedings of the IEEE conference on computer vision and pattern recognition, pp. 7132–7141

  29. He K, Zhang X, Ren S, Sun J (2015) Deep residual learning for image recognition. arXiv preprint arXiv:1512.03385

  30. Howard AG, Zhu M, Chen B, Kalenichenko D, Wang W, Weyand T, Andreetto M, Adam H (2017) Mobilenets: Efficient convolutional neural networks for mobile vision applications. arXiv preprint. Doi: https://doi.org/10.48550/arXiv.1704.04861

Download references

Funding

This study was not supported by any funding.

Author information

Authors and Affiliations

Authors

Contributions

The collaborative efforts of Millee Panigrahi, Rina Mahakud, Santi Kumari Behera, Rasmi Kanta Pati, and Prabira Kumar Sethy have culminated in this research article. Millee Panigrahi played a pivotal role in conceptualization, methodology design, data curation, formal analysis, and the initial drafting of the manuscript. Rina Mahakud contributed significantly to the investigation process, data curation, and provided valuable insights during the writing and editing phases. Santi Kumari Behera's expertise was instrumental in methodological aspects, software implementation, formal analysis, and contributing to the initial draft and visualizations. Rasmi Kanta Pati took charge of conceptualization, resource management, data curation, and played a key role in the critical review and editing of the manuscript. Prabira Kumar Sethy provided overall supervision, participated in the writing and editing process, and ensured the validation of the research outcomes. The final manuscript reflects the combined dedication and diverse skill sets of all authors who have collectively shaped and enriched the research.

Corresponding author

Correspondence to Prabira Kumar Sethy.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

Ethical approval was not required for this study.

Consent to participate

Consent to participate was not required.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Behera, S.K., Mahakud, R., Panigrahi, M. et al. Diagnosis of retinal damage using Resnet rescaling and support vector machine (Resnet-RS-SVM): a case study from an Indian hospital. Int Ophthalmol 44, 174 (2024). https://doi.org/10.1007/s10792-024-03058-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s10792-024-03058-0

Keywords

Navigation