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Choroidal binarization analysis: clinical application

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Abstract

Introduction

Image processing of optical coherence tomography scans through binarization techniques represent a non-invasive way to separately asses and measure choroidal components, in vivo. In this review, we systematically search the scientific literature regarding binarization studies published so far.

Methods

A systematic research was conducted at PubMed database, including English literature articles for all of the following terms in various combinations: binarization, choroid/al, enhanced depth spectral domain/swept source optic coherence tomography, and latest publications up to November 2018 were reviewed.

Results

Thirty-seven articles were included and analyzed regarding studied disease, binarization method, studied variables, and outcomes. Most of the studies have focused on the more common retinal pathologies, such as age-related macular degeneration, central serous chorioretinopathy and diabetic retinopathy but binarization techniques have also been applied to the study of choroidal characteristics in ocular inflammatory diseases, corneal dystrophies and in postsurgical follow-up. Advantages and disadvantages of binarization techniques are also discussed.

Conclusion

Binarization of choroidal images seems to represent a promising approach to study choroid subcomponents in an increasingly detailed manner.

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Authors and Affiliations

  1. Department of Ophthalmology, Central Lisbon Hospital Center, Alameda de Santo António DOS Capuchos, Santo António, 1169-050, Lisbon, Portugal

    Sara Crisostomo, Joana Cardigos, Diogo Hipólito Fernandes, Maria Elisa Luís, Nuno Moura-Coelho, João Paulo Cunha & Joana Ferreira

  2. Department of Ophthalmology, Évora Espirito Santo Hospital, Évora, Portugal

    Ricardo Figueiredo

  3. Department of Ophthalmology, North Lisbon Hospital Center, Lisbon, Portugal

    Luís Abegão Pinto

  4. NOVA Medical School/Faculdade de Ciências Médicas da UNL, Lisbon, Portugal

    João Paulo Cunha & Joana Ferreira

  5. Visual Sciences Study Center, Faculty of Medicine, Lisbon University, Lisbon, Portugal

    Luís Abegão Pinto

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  1. Sara Crisostomo
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Correspondence to Sara Crisostomo.

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Crisostomo, S., Cardigos, J., Fernandes, D.H. et al. Choroidal binarization analysis: clinical application. Int Ophthalmol 39, 2947–2973 (2019). https://doi.org/10.1007/s10792-019-01122-8

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