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Outcomes of same-site re-operation with minimal use of mitomycin in failed trabeculectomy

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Abstract

To evaluate efficacy and safety of same site re-operation in eyes with failed trabeculectomy. A retrospective, noncomparative, interventional case series. We reviewed the medical records of 35 eyes of 35 patients who underwent same-site re-operation for failed trabeculectomy. The surgery involved a fornix-based peritomy at the same site as the previous trabeculectomy with application of 0.2 mg/mL mitomycin for 1 min. Primary outcome measures were intraocular pressure (IOP) control and number of antiglaucoma medications at last follow-up. Success rates were defined according to criteria (A) IOP ≤ 21 mmHg or (B) IOP ≤ 18 mmHg, with or without antiglaucoma medication. The mean age of the patients was 43.3 ± 18.0 years and 62.9 % were male. The mean follow-up was 13.6 ± 12.0 months (range 6−49 months). At final follow-up, mean baseline IOP was reduced from 27.2 ± 8.0 to 16.6 ± 7.5 mmHg (p < 0001). The mean number of antiglaucoma medications was reduced from 2.8 ± 0.8 to 1.0 ± 1.3 (p < 0001). This study supports the efficacy and safety of same-site re-operation with minimal use of mitomycin C for management of failed filtering blebs following trabeculectomy.

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Authors and Affiliations

  1. Eye Research Center, Farabi Eye Hospital, Medical Sciences, Tehran University, Qazvin Square, South Karegar Avenue, Tehran, Iran

    Yadollah Eslami, Vafa Samarai, Massood Mohammadi, Ghasem Fakhraie, Reza Zarei, Sajad Eslami & Sasan Moghimi

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  1. Yadollah Eslami
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  2. Vafa Samarai
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  3. Massood Mohammadi
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  4. Ghasem Fakhraie
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  5. Reza Zarei
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  6. Sajad Eslami
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  7. Sasan Moghimi
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Correspondence to Vafa Samarai.

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Eslami, Y., Samarai, V., Mohammadi, M. et al. Outcomes of same-site re-operation with minimal use of mitomycin in failed trabeculectomy. Int Ophthalmol 34, 501–504 (2014). https://doi.org/10.1007/s10792-013-9840-5

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  • DOI: https://doi.org/10.1007/s10792-013-9840-5

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