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Colonoscopy and chromoscopy in hereditary colorectal cancer syndromes

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Abstract

With hereditary colorectal cancer prevention studies it is difficult to demonstrate reduced mortality. Large populations are needed with well characterized genetics followed over a long period of time. Those studies do exist for standard white light colonoscopy surveillance in Lynch syndrome, but not for newer technologies including chromoscopy. For these newer technologies adenoma detection rate becomes the stand-in for mortality, and the assumption is made that surveillance efficacy impacts cancer occurrence. Though well-designed and important work exists in this area, the data do not support firm conclusions regarding the use of chromoscopy in Lynch syndrome.

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Authors and Affiliations

  1. Department of Gastroenterology, Creighton University, 2500 California Plaza, Criss II, Room 117A, Omaha, NE, 68178, USA

    Erin Jenkins Wessling & Stephen J. Lanspa

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  1. Erin Jenkins Wessling
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  2. Stephen J. Lanspa
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Correspondence to Stephen J. Lanspa.

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The manuscript is a review and did not involve direct patient interactions.

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The authors declare that they have no conflict of interest.

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Jenkins Wessling, E., Lanspa, S.J. Colonoscopy and chromoscopy in hereditary colorectal cancer syndromes. Familial Cancer 15, 453–455 (2016). https://doi.org/10.1007/s10689-016-9881-9

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  • DOI: https://doi.org/10.1007/s10689-016-9881-9

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