Skip to main content

Advertisement

Log in

Prevalence of Irritable Bowel Syndrome and Depression in Fibromyalgia

  • Intestinal Diseases and Irritable Bowel Syndrome
  • Published:
Digestive Diseases and Sciences Aims and scope Submit manuscript

Abstract

The purpose of this study was to determine the point prevalence of depressive symptoms, using the PRIME-MD questionnaire, and irritable bowel syndrome (IBS), while comparing the Rome II to the Rome I criteria, in patients with fibromyalgia (FM) and rheumatologic controls in an outpatient setting. The prevalence of IBS in FM patients (n = 105) was 63% by Rome I and 81% by Rome II criteria. The prevalence of IBS in controls (n = 62) was 15% by Rome I and 24% by Rome II criteria (FM vs. control; P < 0.001). Depressive symptoms were met in 40% of FM patients and 8% of controls (P < 0.001). The coexistence of IBS and depressive symptoms in the FM patients was 31% (Rome I) and 34% (Rome II). The prevalence of IBS and depressive symptoms was higher in FM patients compared to the control population. Identification of IBS and depressive symptoms in FM patients might enable clinicians to better meet the needs of this patient population.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Offenbaecher M, Glatzeder K, Ackenheil M: Self-reported depression, familial history of depression and fibromyalgia (FM), and psychological distress in patients with FM. Z Rheumatol 57 (Suppl 2):94–96, 1998

    Article  PubMed  Google Scholar 

  2. Burckhardt CS, O’Reilly CA, Wiens AN, Clark SR, Campbell SM, Bennett RM: Assessing depression in fibromyalgia patients. Arthritis Care Res 7:35–39, 1994

    CAS  PubMed  Google Scholar 

  3. Vanner SJ, Depew WT, Paterson WG, et al.: Predictive value of the rome criteria for diagnosing the irritable bowel syndrome. Am J Gastroenterol 94:2912–2917, 1999

    Article  CAS  PubMed  Google Scholar 

  4. Pace F, Sarzi-Puttini P, Manzionna G: Visceral hypersensitivity is not a feature of fibromyalgia syndrome. J Musculoskel Pain 9:47–55, 2001

    Article  Google Scholar 

  5. Sperber AD, Atzmon Y, Neumann L, et al.: Fibromyalgia in the irritable bowel syndrome: Studies of prevalence and clinical implications. Am J Gastroenterol 94:3541–3546, 1999

    Article  CAS  PubMed  Google Scholar 

  6. Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Muller-Lissner SA: Functional bowel disorders and functional abdominal pain. Gut 45 (Suppl 2):II43–II47, 1999

    PubMed  Google Scholar 

  7. Ercolani M, Trombini G, Chattat R, et al.: Fibromyalgic syndrome: Depression and abnormal illness behavior. multicenter investigation. Psychother Psychosom 61:178–186, 1994

    CAS  PubMed  Google Scholar 

  8. Spitzer RL, Kroenke K, Williams JB: Validation and utility of a self-report version of PRIME-MD: The PHQ primary care study. Primary care evaluation of mental disorders. Patient health questionnaire. JAMA 282:1737–1744, 1999

    Article  CAS  PubMed  Google Scholar 

  9. Wolfe F, Smythe HA, Yunus MB, et al.: The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. report of the multicenter criteria committee. Arth Rheum 33:160–172, 1990

    CAS  Google Scholar 

  10. Thompson WG, Dotevall G, Drossman DA, Heaton KW: Irritable bowel syndrome: Guidelines for the diagnosis and functional abdominal pain. Gastroenterol Int 2:92–95, 1989

    Google Scholar 

  11. Triadafilopoulos G, Simms RW, Goldenberg DL: Bowel dysfunction in fibromyalgia syndrome. Dig Dis Sci 36:59–64, 1991

    CAS  PubMed  Google Scholar 

  12. Drossman DA, Sandler RS, McKee DC, Lovitz AJ: Bowel patterns among subjects not seeking health care. use of a questionnaire to identify a population with bowel dysfunction. Gastroenterology 83:529–534, 1982

    CAS  PubMed  Google Scholar 

  13. Mearin F, Roset M, Badia X, et al.: Splitting irritable bowel syndrome: From original Rome to Rome II criteria. Am J Gastroenterol 99:122–130, 2004

    PubMed  Google Scholar 

  14. Mearin F, Balboa A, Badia X, et al.: Irritable bowel syndrome subtypes according to bowel habit: Revisiting the alternating subtype. Eur J Gastroenterol Hepato 115:165–172, 2003

    Google Scholar 

  15. Katon W, Schulberg H: Epidemiology of depression in primary care. Gen Hosp Psychiatry 14:237–247, 1992

    CAS  PubMed  Google Scholar 

  16. Rush J, Hay B: Depression guideline panel: Depression in primary care, detection and diagnosis, clinical practice guideline. AHCPR 1, 1993

  17. Abdel-Nasser AM, Abd El-Azim S, Taal E, El-Badawy SA, Rasker JJ, Valkenburg HA: Depression and depressive symptoms in rheumatoid arthritis patients: An analysis of their occurrence and determinants. Br J Rheumatol 37:391–397, 1998

    Article  CAS  PubMed  Google Scholar 

  18. Soderlin MK, Hakala M, Nieminen P: Anxiety and depression in a community-based rheumatoid arthritis population. Scand J Rheumatol 29:177–183, 2000

    CAS  PubMed  Google Scholar 

  19. Boyce PM, Koloski NA, Talley NJ: Irritable bowel syndrome according to varying diagnostic criteria: Are the new rome II criteria unnecessarily restrictive for research and practice? Am J Gastroenterol 95:3176–3183, 2000

    CAS  PubMed  Google Scholar 

  20. Giesecke T, Williams DA, Harris RE, et al.: Subgrouping of fibromyalgia patients on the basis of pressure-pain thresholds and psychological factors. Arth Rheum 48:2916–2922, 2003

    Google Scholar 

  21. Chang L: The association of functional gastrointestinal disorders and fibromyalgia. Eur J Surg Suppl 583:32–36, 1998

    PubMed  Google Scholar 

  22. Mertz H, Morgan V, Tanner G, et al.: Regional cerebral activation in irritable bowel syndrome and control subjects with painful and nonpainful rectal distention. Gastroenterology 118:842–848, 2000

    Article  CAS  PubMed  Google Scholar 

  23. Silverman DH, Munakata JA, Ennes H, Mandelkern MA, Hoh CK, Mayer EA: Regional cerebral activity in normal and pathological perception of visceral pain. Gastroenterology 112:64–72, 1997

    Article  CAS  PubMed  Google Scholar 

  24. Chang L, Berman S, Mayer EA, et al.: Brain responses to visceral and somatic stimuli in patients with irritable bowel syndrome with and without fibromyalgia. Am J Gastroenterol 98:1354–1361, 2003

    Article  PubMed  Google Scholar 

  25. Pimentel M, Wallace D, Hallegua D, et al.: A link between irritable bowel syndrome and fibromyalgia may be related to findings on lactulose breath testing. Ann Rheum Dis 63:450–452, 2004

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jayde E. Kurland MD, FACP.

Additional information

The views expressed in this article are those of the authors and do not reflect the official policy or practice of the Department of the Navy, Department of Defense, or the United States Government. This research was performed at outpatient private rheumatology clinics. No financial support was received for the research

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kurland, J.E., Coyle, W.J., Winkler, A. et al. Prevalence of Irritable Bowel Syndrome and Depression in Fibromyalgia. Dig Dis Sci 51, 454–460 (2006). https://doi.org/10.1007/s10620-006-3154-7

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10620-006-3154-7

Key Words

Navigation