Skip to main content

Advertisement

Log in

Effectiveness of fresh frozen and cryopreserved homologue iliac crest grafts used in sinus lifting: a comparative study

  • Original Paper
  • Published:
Cell and Tissue Banking Aims and scope Submit manuscript

Abstract

In the last decade, several investigators have reported that autologous and homologous fresh frozen bones (FFB) are effective materials to restore alveolar ridges previous to insert dental implants. Recently we have used cryopreserved homologue grafts (CFFB). Here we reported a retrospective comparative study between implants inserted in FFB and CFFB evaluate their clinical outcome. Patients were treated with a split mouth scheme for bone grafting with FFB and CFFB and spiral family implants (SPI) were inserted in the same surgical time. Several variables (patient, grafts, anatomic site, implant, prosthetic restoration) were investigated. Implant’ failure and peri-implant bone resorption were considered as predictor of clinical outcome. A total of 84 SFIs were inserted in 12 patients. Implants were inserted to replace 8 incisors, 4 cuspids, 31 premolars and 41 molars. The mean follow-up was 14 months. Three out of 84 implants was lost (i.e. survival rate SVR = 96.4%) and no differences were detected among the studied variables. Similar result was obtained by analyzing the crestal bone resorption around implant’ neck (i.e. success rate). FFB and CFFB have high and comparable survival and success rate. Implants inserted with one step surgical procedure in native (i.e. not grafted) bone, FFB and CFFB have similar clinical outcome.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9

Similar content being viewed by others

References

  • Albrektsson T, Zarb GA (1998) Determinants of correct clinical reporting. Int J Prostodont 11:517–521

    CAS  Google Scholar 

  • Carinci F, Farina A, Zanetti U, Vinci R, Negrini S, Calura G, Laino G, Piattelli A (2005) Alveolar ridge augmentation: a comparative longitudinal study between calvaria and iliac crest bone grafts. J Oral Implantol 31:39–45

    Article  PubMed  Google Scholar 

  • Carinci F, Brunelli G, Franco M, Viscioni A, Rigo L, Guidi R, Strohmenger L (2008) A retrospective study on 287 implants installed in resorbed maxillae grafted with fresh frozen allogenous bone. Clin Implant Dent Relat Res 12:91–98

    Article  PubMed  Google Scholar 

  • Carinci F, Brunelli G, Zollino I, Franco M, Viscioni A, Rigo L, Guidi R, Strohmenger L (2009) Mandibles grafted with fresh-frozen bone: an evaluation of implant outcome. Implant Dent 18:86–95

    Article  PubMed  Google Scholar 

  • Cox DR, Oakes D (1984) Analysis of survival data. Chapman & Hall, New York

    Google Scholar 

  • Dawson-Saunders B, Trapp RG (1994) Basic and clinical biostatistic. Appleton & Lange, Norwalk

    Google Scholar 

  • Egli RJ, Sckell A, Fraitzl CL, Feli R, Ganz R, Leunig M (2003) Cryopreservation with dimehtyl sulfoxide sustains partially the biological function of osteochondral tissue. Bone 33:352–361

    Article  PubMed  CAS  Google Scholar 

  • Egli RJ, Wingenfeld C, Holzle M, Hempfing A, Fraitzl CR, Ganz R, Leunig M (2006) Histopathology of cryopreserved bone allo- and isograft: pretreatment with dimehtyl sulfoxide. J Invest Surg 19:87–96

    Article  PubMed  CAS  Google Scholar 

  • Franco M, Viscioni A, Rigo L, Guidi R, Brunelli G, Carinci F (2008a) Iliac crest fresh frozen homografts used in pre-prosthetic surgery: a retrospective study. Cell Tissue Bank 10:227–233

    Article  PubMed  Google Scholar 

  • Franco M, Tropina E, De Santis B, Viscioni A, Rigo L, Guidi R, Carinci F (2008b) A 2-year follow-up study on standard length implants inserted into alveolar bone sites augmented with homografts. Stomatologija 10:127–132

    PubMed  Google Scholar 

  • Gajiwala K, Lobo Gajiwala A (2003) Use of banked tissue in plastic surgery. Cell Tissue Bank 4:141–146

    Article  PubMed  Google Scholar 

  • Perrot DH, Smith RA, Kaban LB (1992) The use of fresh frozen allogenic bone for maxillary and mandibular reconstruction. Int J Oral Maxillofac Surg 21:260–265

    Article  Google Scholar 

  • Quirynen M, van Steenberghe D, Jacobs R, Schotte A, Darius P (1991a) The reliability of pocket probing around screw-type implants. Clin Oral Impl Res 2:186–192

    Article  CAS  Google Scholar 

  • Quirynen M, Naert I, van Steenberghe D, Teerlinck J, Dekeyser C, Theuniers G (1991b) Periodontal aspects of osseointegrated fixtures supporting an overdenture. A 4-year retrospective study. J Clin Periodontol 18:719–728

    Article  PubMed  CAS  Google Scholar 

  • Reuther T, Rohmann D, Scheer M, Kubler AC (2005) Osteoblast viability and differentiation with Me2SO as cryoprotectant compared to osteoblasts from fresh human iliac cancellous bone. Cryobiology 51:311–321

    Article  PubMed  CAS  Google Scholar 

  • Rochanawutanon S (2002) Long term follow up of reconstruction of allogenic mandibular bone crib packed with autogenous particulate cancellous bone marrow. Cell Tissue Bank 3:183–197

    Article  PubMed  Google Scholar 

  • Tomford WW, Mankin HJ (1999) Bone banking. Update on methods, materials. Orthop Clin North Am 30:565–570

    Article  PubMed  CAS  Google Scholar 

  • Vangsness CT Jr, Garcia IA, Mills CR, Kainer MA, Roberts MR, Moore TM (2003) Allograft transplantation in the knee: tissue regulation, procurement, processing, and sterilization. Am J Sports Med 31:474–481

    PubMed  Google Scholar 

  • Vargel I, Tunçbilek G, Mavili E, Cila A, Ruacan S, Benli K, Erk Y (2004) Solvent-dehydrated calvarial allografts in craniofacial surgery. Plast Reconstr Surg 114:298–306

    Article  PubMed  Google Scholar 

  • Viscioni A, Franco M, Rigo L, Guidi R, Spinelli G, Carinci F (2009) Retrospective study of standard-diameter implants inserted into allografts. J Oral Maxillofac Surg 67:387–393

    Article  PubMed  Google Scholar 

  • Wingenfeld C, Egli RJ, Hempfing A, Ganz R, Leunig M (2002) Cryopreservation of osteochondral allografts: dimethyl sulfoxide promotes angiogenesis and immune tollerance in mice. J Bone Joint Surg Am 84:1420–1429

    PubMed  Google Scholar 

Download references

Acknowledgment

This work was supported by FAR from the University of Ferrara (FC), Ferrara, Italy, and from Regione Emilia Romagna, Programma di Ricerca Regione Universita, 2007–2009, Area 1B: Patologia osteoarticolare: ricerca pre-clinica e applicazioni cliniche della medicina rigenerativa Unita Operativa n. 14, and PRIN 2008 (F.C.).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Francesco Carinci.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Viscioni, A., Franco, M., Paolin, A. et al. Effectiveness of fresh frozen and cryopreserved homologue iliac crest grafts used in sinus lifting: a comparative study. Cell Tissue Bank 12, 263–271 (2011). https://doi.org/10.1007/s10561-010-9192-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10561-010-9192-6

Keywords

Navigation