Abstract
Atrial high-rate episodes (AHRE) defined as atrial tachy-arrhythmias, detected through continuous monitoring with a cardiac implantable electronic device (CIED). AHRE’s have been associated with increased risks of developing clinically manifested atrial fibrillation, thromboembolism, cardiovascular events, and mortality. Several variables have been researched and identified to predict AHRE existence. The present study evaluated the association between right-heart structural and functional echocardiographic parameters and AHRE in patients with CIEDs and impaired LVEF. This prospective design study included 194 patients with CIED’s. The study population was divided into two groups according to presence of AHRE and analyzed the echocardiographic variables which may able to be a predictor of AHRE. Patients was divided into two groups: patients with AHRE (+) and without AHRE (–). The distribution of patients’ characteristics according to presence of AHRE was analyzed. The multivariate analysis revealed Age, LAVI, E/Em tricuspid (HR: 1.106, 1.015–1.205% 95 CI; p = 0.022) and RAVI (HR: 1.035, 1.003–1.069 95% CI; p = 0.033) as independent predictors of AHREs. ROC curve analysis indicated that an E/Em tricuspid (AUC: 0.611, 95% CI 0.538–0.680 p: 0.009) and RAVI (AUC = AUC: 0.707, 95% CI 0.637–0.770 p < 0.001) predicted AHREs with a cut-off value of 6.28 and a sensitivity of 53.2% and specificity of 66.7% and a cut-off value of 29.5 mL/m2 with a sensitivity of 72.7% and a specificity of 65.9%, respectively. The main finding of this study was “RAVI” and “E/Emtricuspid ratio” is associated with AHRE. Additionally, “RAVI” and “E/Emtricuspid ratio” is an independent predictor of AHRE existence.
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IA and IR contributed to the study conception and design. Echocardiographic analysis were performed by IA, MK and AA. IA, TO, MHS and DI enrolled patients and performed follow-up in the main studies and assisted in interpretation of results. IR assisted in interpretation of results and YK supervised the statistics. The first draft of the manuscript was written by IA and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
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Artac, I., Karakayali, M., Omar, T. et al. The impact of the right heart cavities echocardiographic features on atrial-high rate episodes. Int J Cardiovasc Imaging 40, 321–330 (2024). https://doi.org/10.1007/s10554-023-02990-z
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DOI: https://doi.org/10.1007/s10554-023-02990-z