Abstract
To examine secular trends in the incidence and mortality of gastric cancer in a Japanese community, Hisayama, we established three study-cohorts of Hisayama residents aged ≥40 years in 1961 (1637 subjects), 1974 (2054), and 1988 (2602). Each cohort was followed up for ten years. The age-standardized mortality from gastric cancer significantly decreased from 2.4 per 1000 person-years in the first cohort to 0.8 in the third cohort for men, and from 1.0 to 0.2, respectively, for women (p < 0.01 for trend in both sexes). The five-year survival rate after gastric cancer significantly improved from the first (32.6%) to the third cohort (73.0%, p < 0.01) for men and from 43.2% to 72.3% (p < 0.05), respectively, for women. The age-standardized incidence of cancer in men was not different among the cohorts (4.3 per 1000 person-years in the first, 5.0 in the second, and 4.9 in the third cohort), while it decreased significantly in women (2.0, 1.8, and 1.2, respectively, p < 0.01 for trend). In conclusion, our findings suggest that in a Japanese population, the mortality from gastric cancer declined during the past 40 years, due mainly to the improvement of survival in both sexes and a decrease in the incidence for women.
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References
DM Parkin SL Whelan J Ferlay L Raymond J Young (Eds) (1997) Cancer incidence in Five Continents International Agency for Research on Cancer Lyon
R Lambert A Guilloux A Oshima et al. (2002) ArticleTitleIncidence and mortality from stomach cancer in Japan, Slovenia and the USA Int J Cancer 97 811–818 Occurrence Handle1:CAS:528:DC%2BD38XhtVShs7s%3D Occurrence Handle11857360
S Tominaga (1987) ArticleTitleDecreasing trend of stomach cancer in Japan Jpn J Cancer Res 78 1–10 Occurrence Handle1:STN:280:BiiC3snpsVM%3D Occurrence Handle3102432
JA Akoh IM Macintyre (1992) ArticleTitleImproving survival in gastric cancer: review of 5-year survival rates in English language publications from 1970 Br J Surg 79 293–299 Occurrence Handle1:STN:280:By2B2cfjvFA%3D Occurrence Handle1576492
Nakamura K, Ueyama T, Yao, et al. (1992) Pathology and prognosis of gastric carcinoma. Findings in 10,000 patients who underwent primary gastrectomy. Cancer 70: 1030–1037
S Hisamichi (1989) ArticleTitleScreening for gastric cancer World J Surg 13 31–37 Occurrence Handle1:STN:280:BiaB28fnvFw%3D Occurrence Handle2658351
The Research Group for Population-based Cancer Registration in Japan (1998) Cancer incidence in Japan, 1985–89: re-estimation based on data from eight population-based cancer registries. Jpn J Clin Oncol 28: 54–67
A Hanai T Kitagawa W Ajika H Tsukuma A Oshima (1998) ArticleTitleCancer incidence in Japan in 1990:estimates based on data from Population-based Cancer Registries. The Research Group for Population-based Cancer Registration in Japan Jpn J Clin Oncol 28 450–453 Occurrence Handle1:STN:280:DyaK1cvht1Wisw%3D%3D Occurrence Handle9739788
CT Schrijvers K Stronks DH Mheen Particlevan de JW Coebergh JP Mackenbach (1994) ArticleTitleValidation of cancer prevalence data from a postal survey by comparison with cancer registry records Am J Epidemiol 139 408–414 Occurrence Handle1:STN:280:ByuC2M3msVA%3D Occurrence Handle8109575
S Katsuki (1966) ArticleTitleEpidemiological and clinicopathological study on cerebrovascular disease in Japan Prog Brain Res 21 64–89 Occurrence Handle1:STN:280:CCiD3MznsV0%3D Occurrence Handle5917289
T Ohmura K Ueda Y Kiyohara et al. (1993) ArticleTitlePrevalence of type 2 (non-insulin-dependent) diabetes mellitus and impaired glucose tolerance in the Japanese general population: the Hisayama Study Diabetologia 36 1198–1203 Occurrence Handle10.1007/BF00401066 Occurrence Handle1:STN:280:ByuD1MrgsFw%3D Occurrence Handle8270136
H Yamagata Y Kiyohara K Aoyagi et al. (2000) ArticleTitleImpact of Helicobacter pylori infection on gastric cancer incidence in a general Japanese population: the Hisayama study Arch Intern Med 160 1962–1968 Occurrence Handle10.1001/archinte.160.13.1962 Occurrence Handle1:STN:280:DC%2BD3czkslKnsA%3D%3D Occurrence Handle10888970
K Ueda T Omae Y Hirota et al. (1981) ArticleTitleDecreasing trend in incidence and mortality from stroke in Hisayama residents, Japan Stroke 12 154–160 Occurrence Handle1:STN:280:Bi6B3c7mslw%3D Occurrence Handle7233458
M Fujishima Y Kiyohara I Kato et al. (1996) ArticleTitleDiabetes and cardiovascular disease in a prospective population survey in Japan: the Hisayama Study Diabetes 45 IssueIDSuppl 3 S14–S16 Occurrence Handle1:CAS:528:DyaK28XjvFartL8%3D
DR Cox (1972) ArticleTitleRegression models and life-tables J R Stat Soc 34 187–220
A Kamineni MA Williams SM Schwartz LS Cook NS Weiss (1999) ArticleTitleThe incidence of gastric carcinoma in Asian migrants to the United States and their descendants Cancer Causes Control 10 77–83 Occurrence Handle10.1023/A:1008849014992 Occurrence Handle1:STN:280:DyaK1M3msFyitw%3D%3D Occurrence Handle10334646
AE Cavelaars AE Kunst JJ Geurts et al. (2000) ArticleTitleEducational differences in smoking: international comparison BMJ 320 1102–1107 Occurrence Handle10.1136/bmj.320.7242.1102 Occurrence Handle1:STN:280:DC%2BD3c3jslemsQ%3D%3D Occurrence Handle10775217
T Shirota A Magome N Miyamoto et al. (1999) ArticleTitleChanges of nutrient intakes and food consumption structure over a 30-years period in Hisayama Bulletin of Nakamura Gakuen College & Nakamura Gakuen Junior College 31 141–151
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Tanaka, K., Kiyohara, Y., Kubo, M. et al. Secular trends in the incidence, mortality, and survival rate of gastric cancer in a general Japanese population: the Hisayama study. Cancer Causes Control 16, 573–578 (2005). https://doi.org/10.1007/s10552-004-7839-y
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DOI: https://doi.org/10.1007/s10552-004-7839-y