Abstract
Cell suspension cultures of five plants (Catharanthus roseus, Ginkgo biloba, Platycodon grandiflorum, Taxus cuspidata, Phytolacca asinosa) were employed to bioconvert the eudesmanolide compound, α-santonin. Reactions occurring were hydroxylation (C-1, C-11 and C-15), reduction of the double bond [1(2) or 3(4)], rearrangment of the eudesmanolide skeleton to a guaianolide skeleton and lactone-ring hydrolysis. Four new compounds were identified.
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Yang, L., Dai, J., Sakai, J. et al. Biotransformation of α-Santonin by Cell Suspension Cultures of Five Plants. Biotechnol Lett 27, 793–797 (2005). https://doi.org/10.1007/s10529-005-5800-0
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DOI: https://doi.org/10.1007/s10529-005-5800-0