Abstract
IGFBP-5 is a member of the IGF families. Using PCR-SSCP, genotypic and allelic frequencies were analyzed in 18 pig breeds (n = 600). The association between haplotypes and production performance was analyzed in a Jinhua × Pietrain population family (n = 212, total 24 traits). Two SNPs (T199C and G485A) within the gene were analyzed. The breeds had different genotypic and allelic frequencies. Typically, the Chinese native pig breeds carried a higher allele C and G frequency (over 50%) than those of the European pigs, and only Guangdong Large White and wild boar were at Hardy–Weinberg equilibrium. The pigs carrying the CG haplotype had higher hue, loin, and thigh pH1 values than pigs with the TA haplotype, and pigs with the TA haplotype had the lowest loin pH2 value and highest color-a value among the haplotypes. It is proposed that the IGFBP-5 gene is associated with the variation in meat quality, especially in pH value together with other QTLs on chromosome 15.
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Acknowledgments
This study was supported by the State Key Basic Research and Development Program (G200000161) and Doctoral Initiation Fund of Jiangxi Agricultural University. The authors thank Prof. Xu Ningyin, Zhejiang University, Zhejiang, P. R. China, for his kind donation of the Jinhua × Pietrain population family.
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Wang, W., Ouyang, K., Shangguan, X. et al. Association of Porcine IGF Binding Protein-5 Gene with Meat Quality. Biochem Genet 48, 257–265 (2010). https://doi.org/10.1007/s10528-009-9315-6
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DOI: https://doi.org/10.1007/s10528-009-9315-6