We studied the reaction of rat hippocampal microgliocytes to hyperbaric oxygen at a pressure of 5 ata (absolute atmosphere). Immunohistochemical analysis with selective macrophage marker CD68 (ED1) and microglial marker Iba-1 allowed separate analysis of these two cell populations. It was shown that macrophages do not significantly contribute to reactive changes in the total pool of Iba-1+ hippocampal cells induced by hyperbaric oxygen.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 173, No. 5, pp. 626-631, May, 2022
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Kirik, O.V., Alekseeva, O.S., Tsyba, D.L. et al. Reaction of the Hippocampal Microglia to Hyperbaric Oxygen. Bull Exp Biol Med 173, 655–659 (2022). https://doi.org/10.1007/s10517-022-05607-y
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DOI: https://doi.org/10.1007/s10517-022-05607-y