We studied the effects of afobazole on apoptosis through active caspase-3. Afobazole in a final concentration of 10–8 M inhibits hyperactivation of effector apoptotic caspase-3 in HT-22 cell culture under conditions of glutamate toxicity.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 149, No. 2, pp. 161-164, February, 2010
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Antipova, T.A., Sapozhnikova, D.S., Stepanichev, M.Y. et al. Effects of Selective Anxiolytic Afobazole on Active Caspase-3. Bull Exp Biol Med 149, 201–203 (2010). https://doi.org/10.1007/s10517-010-0907-2
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DOI: https://doi.org/10.1007/s10517-010-0907-2