We studied the formation and cytophysiological characteristics of polynuclear macrophages in primary cultures of peritoneal cells from C57Bl/6 mice. Production of reactive oxygen species and phagocytic activity in polynuclear macrophages were higher than in mononuclear macrophages. The formation of polynuclear macrophages in cultures of peritoneal cells is realized via amitosis.
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References
S. A. Arkhipov, Epithelioid Cell. New Conception of the Origin and Differentiation [in Russian], Novosibirsk (1997).
S. A. Arkhipov, Byull. Sib. Otd. Ros. Akad. Med. Nauk, Nos. 3–4, 123–127 (2000).
A. G. Bulychev, Segregation Function of the Cell [in Russian], Leningrad (1991).
E. D. Gol’dberg, A. M. Dygai, and V. P. Shakhov, Tissue Culture Methods in Hematology [in Russian], Tomsk (1992).
V. A. Shkurupiy, M. A. Kozyaev, and A. P. Nadeev, Byull. Eksp. Biol. Med., 141, No. 4, 474–477 (2006).
V. A. Shkurupiy, Yu. N. Kurunov, and N. N. Yakovchenko, Lysosomotropism. Problems of Cellular Physiology and Medicine [in Russian], Novosibirsk (1999).
H. David and I. Uerlings, Zentralbl. Pathol., 138, No. 4, 278–283 (1992).
F. Facchetti, W. Vermi, S. Fiorentini, et al., Am. J. Pathol., 154, No. 1, 145–152 (1999).
A. Gasser and J. Most, Infect. Immun., 67, No. 1, 395–402 (1999).
A. K. McNally and J. M. Anderson, Am. J. Pathol., 163, No. 3, 1147–1156 (2003).
R. J. Menaker, P. J. Ceponis, and N. L. Jones, Infect. Immun., 72, No. 5, 2889–2898 (2004).
C. W. Michael and A. Flint, Am. J. Clin. Pathol., 110, No. 1, 10–15 (1998).
K. Sorimachi, H. Naora, K. Akimoto, et al., Cell Biol. Int., 22, No. 5, 351–357 (1998).
K. Suzuki, T. Izumi, T. Iwanaga, et al., Arch. Histol. Cytol., 58, No. 2, 231–241 (1995).
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Suppl. 1, pp. 89–92, 2008
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Arkhipov, S.A., Shkurupiy, V.A., Ijine, D.A. et al. Formation and Some Cytophysiological Characteristics of Polynuclear Macrophages in Primary Cultures of Peritoneal Cells. Bull Exp Biol Med 146, 838–841 (2008). https://doi.org/10.1007/s10517-009-0405-6
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DOI: https://doi.org/10.1007/s10517-009-0405-6