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Neurotropic effects of L-lysine in formation of pain-induced behavior

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Abstract

In experiments on Wistar rats L-lysine (0.15, 0.5, 1.5, 5.0, 15.0, and 50.0 µg/kg intraperitoneally) exhibited a dose-dependent algic effect during electrocutaneous stimulation of the tail and dose-dependent effects in aggressive defense behavior caused by electrical painful stimulation of paws. It was found that the effect of L-lysine depended on situation determining the predominance of defense or aggression, rather than on the intensity of painful stimulation.

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Authors and Affiliations

  1. Department of Pathophysiology, Kursk State Medical University, Kursk, Russia

    L. A. Severyanova, M. E. Dolgintsev, I. I. Bobyntsev & A. A. Kryukov

Authors
  1. L. A. Severyanova
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  2. M. E. Dolgintsev
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  3. I. I. Bobyntsev
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  4. A. A. Kryukov
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Corresponding author

Correspondence to L. A. Severyanova.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 145, No. 5, pp. 529–532, May, 2008

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Severyanova, L.A., Dolgintsev, M.E., Bobyntsev, I.I. et al. Neurotropic effects of L-lysine in formation of pain-induced behavior. Bull Exp Biol Med 145, 592–594 (2008). https://doi.org/10.1007/s10517-008-0139-x

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  • DOI: https://doi.org/10.1007/s10517-008-0139-x

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