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Atopy parameters in asthmatic children increase with accumulation of null-alleles of glutathione-S-transferase M1

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Abstract

Atopy parameters (total IgE, skin prick test, and peripheral blood eosinophil count) in children with atopic bronchial asthma depend on the number of glutathione-S-transferase M1 mutant alleles in the genotype and on family history of asthma.

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Authors and Affiliations

  1. Institute of Molecular Biology and Biophysics, Siberian Division of Russian Academy of Medical Sciences, Russia

    S. I. Makarova, O. G. Safronova, V. A. Vavilin & V. V. Lyakhovich

  2. Novosibirsk State Medical Academy, Russia

    O. A. Batychko & S. M. Gavalov

Authors
  1. S. I. Makarova
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  2. O. G. Safronova
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  3. V. A. Vavilin
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  4. O. A. Batychko
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  5. S. M. Gavalov
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  6. V. V. Lyakhovich
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Corresponding author

Correspondence to S. I. Makarova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 138, No. 11, pp. 520–522, November, 2004

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Makarova, S.I., Safronova, O.G., Vavilin, V.A. et al. Atopy parameters in asthmatic children increase with accumulation of null-alleles of glutathione-S-transferase M1. Bull Exp Biol Med 138, 460–462 (2004). https://doi.org/10.1007/s10517-005-0070-3

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  • DOI: https://doi.org/10.1007/s10517-005-0070-3

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