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Detrimental effect of deltamethrin on the central nervous system (synganglion) of Rhipicephalus sanguineus ticks

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Abstract

Ticks are ectoparasites of medical and veterinary importance, which transmit many infectious agents, causing significant damage to the hosts. The “dog tick” Rhipicephalus sanguineus is responsible for transmitting several pathogens to dogs, motivating researchers to investigate efficient and sustainable control methods. Currently, chemical acaricides currently in use target the central nervous system (synganglion), which is responsible for controlling all the systemic functions of the ticks. Here, the neurotoxic potential of deltamethrin on the synganglion of unfed R. sanguineus female ticks was investigated. The results showed that the synganglion of the females belonging to the control group presented intact morphological characteristics; however, the ones from the treatment group (exposed to 1.5, 3.12 and 6.25 ppm of deltamethrin) displayed alterations, which were increasingly intense as the concentration increased. Observed alterations were mainly in the cortex region and in the neuropile, indicating that the deltamethrin is neurotoxic.

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Acknowledgments

The authors are grateful to the Fundação de Amparo à Pesquisa do Estado de São Paulo-FAPESP (Grant: 2015/20745-6) and to the Conselho Nacional de Desenvolvimento Científico e Tecnológico-CNPq (Grant: 300625/2012-0), M.I. Camargo-Mathias academic carrier research fellowship for the financial support. The authors would like to thank Mr. Gerson de Mello Sousa for technical support.

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Authors and Affiliations

  1. Sao Paulo State University (UNESP) “Júlio de Mesquita Filho”, Avenida 24 A, 1515, Rio Claro, SP, 13506-900, Brazil

    Melissa Carolina Pereira, Ana Elisa Gasparotto, Juliana Paneczko Jurgilas, Letícia Aurora Coelho da Silva, Mayara Cristina Pereira, Samantha Santos Silveira, Thays Neigri Silva, André Arnosti & Maria Izabel Camargo-Mathias

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  1. Melissa Carolina Pereira
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  2. Ana Elisa Gasparotto
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  3. Juliana Paneczko Jurgilas
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  4. Letícia Aurora Coelho da Silva
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  5. Mayara Cristina Pereira
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  6. Samantha Santos Silveira
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  8. André Arnosti
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  9. Maria Izabel Camargo-Mathias
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Correspondence to Maria Izabel Camargo-Mathias.

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Pereira, M.C., Gasparotto, A.E., Jurgilas, J.P. et al. Detrimental effect of deltamethrin on the central nervous system (synganglion) of Rhipicephalus sanguineus ticks. Exp Appl Acarol 71, 159–169 (2017). https://doi.org/10.1007/s10493-017-0109-y

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