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Efficacy of Neurofeedback Versus Pharmacological Support in Subjects with ADHD

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Abstract

Behavioral training in neurofeedback has proven to be an essential complement to generalize the effects of pharmacological support in subjects who have attention deficit with hyperactivity disorder (ADHD). Therefore, this investigation attempts to analyze the efficacy of neurofeedback compared with pharmacological support and the combination of both. Participants were 131 students, classified into four groups: control (did not receive neurofeedback or pharmacological support), neurofeedback group, pharmacological support group, and combined group (neurofeedback + pharmacological support). Participants’ executive control and cortical activation were assessed before and after treatment. Results indicate that the combined group obtained more benefits and that the neurofeedback group improved to a greater extent in executive control than the pharmacological support group. It is concluded that this kind of training may be an alternative to stimulate activation in subjects with ADHD.

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References

  • Álvarez, L., González-Castro, P., Núñez, J. C., González-Pienda, J. A., & Bernardo, A. (2008). Evaluacion y control de la activacion cortical en los deficit de atencion sostenida [Assessment and control of cortical activation in sustained attention deficits]. International Journal of Clinical and Health Psychology, 8(2), 509–524.

    Google Scholar 

  • American Psychiatric Association, APA. (1987). Diagnostic and statistical manual of mental disorders (3rd ed.). Washington, DC: Author.

    Google Scholar 

  • American Psychiatric Association, APA. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author.

    Google Scholar 

  • Arns, M., Drinkenburg, W., & Leon-Kenemans, J. (2012). The effects of QEEG-informed neurofeedback in ADHD: An open-label pilot study. Applied Psychophysiology and Biofeedback, 37(3), 171–180. doi:10.1007/s10484-012-9191-4.

    Article  PubMed Central  PubMed  Google Scholar 

  • Bakhshayesh, A. R., Hänsch, S., Wyschkon, A., Java-Rezai, M., & Esser, G. (2011). Neurofeedback in ADHD: A single-blind randomized controlled trial. European Child and Adolescent Psychiatry, 20(9), 481–491. doi:10.1007/s00787-011-0208-y.

    Article  PubMed  Google Scholar 

  • Brickenkamp, R. (2002). D-2 Test de atención. Adaptación española. Madrid: TEA Ediciones.

    Google Scholar 

  • Christiansen, H., Reh, V., Schmidt, M. H., & Rief, W. (2014). Slow cortical potential neurofeedback and self-management training in outpatient care for children with ADHD: Study protocol and first preliminary results of a randomized controlled trial. Frontiers in Human Neuroscience, 8, 1–15. doi:10.3389/fnhum.2014.00943.

    Google Scholar 

  • Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). New Jersey: Lawrence Erlbaum.

    Google Scholar 

  • Congedo, M., & Lubar, J. F. (2003). Parametric and non-parametric analysis of QEEG: Normative database comparisons in electroencephalography, a simulation study on accuracy. Journal of Neurotherapy, 7(3), 1–29. doi:10.1300/J184v07n03_01.

    Article  Google Scholar 

  • Duric, N. S., Abmus, J., & Elgen, I. B. (2014). Self-reported efficacy of neurofeedback treatment in a clinical randomized controlled study of ADHD children and adolescents. Neuropsychiatric Disease and Treatment, 10, 1645–1654. doi:10.2147/NDT.S66466.

    Article  PubMed Central  PubMed  Google Scholar 

  • Farré, A., & Narbona, J. (2013). Scale of attention deficit and hyperactivity (7th ed.). Madrid: TEA Ediciones.

    Google Scholar 

  • Fuchs, T., Birbaumer, N., Lutzenberger, W., Gruzelier, J. H., & Kaiser, J. (2003). Neurofeedback treatment for attention-deficit/hyperactivity disorder in children: A comparison with methylphenidate. Applied Psychophysiology and Biofeedback, 28(1), 1–12.

    Article  PubMed  Google Scholar 

  • Gevensleben, H., Holl, B., Albrecht, B., Schlamp, D., Kratz, O., Studer, P., & Heinrich, H. (2010). Neurofeedback training in children with ADHD: 6-month follow-up of a randomised controlled trial. European Child and Adolescent Psychiatry, 19(9), 715–724. doi:10.1007/s00787-010-0109-5.

    Article  PubMed Central  PubMed  Google Scholar 

  • Gevensleben, H., Holl, B., Albrecht, B., Vogel, C., Schlamp, D., Kratz, O., & Heinrich, H. (2009). Is neurofeedback an efficacious treatment for ADHD? A randomised controlled clinical trial. The Journal of Child Psychology and Psychiatry, 50(7), 780–789. doi:10.1111/j.1469-7610.2008.02033.x.

    Article  PubMed  Google Scholar 

  • González-Castro, P., Rodríguez, C., López, A., Cueli, M., & Álvarez, L. (2013). Attention deficit hyperactivity disorder, differential diagnosis with blood oxygenation, beta/theta ratio, and attention measures. International Journal of Clinical and Health Psychology, 13(2), 101–109. doi:10.1016/S1697-2600(13)70013-9.

    Article  Google Scholar 

  • Greenberg, M. L. (1996). Test of variables of attention (TOVA-TOVA-A). Los Alamitos, CA: U.A.D.

    Google Scholar 

  • Holtmann, M., Sonuga-Barke, E., Cortese, S., & Brandeis, D. (2014). Neurofeedback for ADHD: A review of current evidence. Child and Adolescent Psychiatric Clinics of North America, 23(4), 789–806. doi:10.1016/j.chc.2014.05.006.

    Article  PubMed  Google Scholar 

  • Lansbergen, M. M., Arns, M., Van Dongen-Boomsma, M., Spronk, D., & Buitelaar, J. K. (2011). The increase in theta/beta ratio on resting-state EEG in boys with attention-deficit/hyperactivity disorder is mediated by slow alpha peak frequency. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 35(1), 47–52. doi:10.1016/j.pnpbp.2010.08.004.

    Article  PubMed  Google Scholar 

  • Lubar, J. F., Swartwood, M. O., Swartwood, J. N., & O’Donnell, P. (1995). Evaluation of the effectiveness of EEG neurofeedback training for ADHD in a clinical setting as measured by changes in TOVA scores, behavioral ratings, and WISK-R performance. Biofeedback and Self-Regulation, 20(1), 83–99.

    Article  PubMed  Google Scholar 

  • Martínez-León, N. C. (2006). Psicopatologia del trastorno por deficit atencional e hiperactividad [Psychopathology of attention deficit and hyperactivity disorder]. International Journal of Clinical and Health Psychology, 6(2), 379–399.

    Google Scholar 

  • Maurizio, S., Liechti, M. D., Brandeis, D., Jäncke, L., & Drechsler, R. (2013). Differential EMG biofeedback for children with ADHD: A control method for neurofeedback training with a case illustration. Applied Psychophysiology Biofeedback, 38(2), 109–119. doi:10.1007/s10484-013-9213-x.

    Article  PubMed  Google Scholar 

  • Mayer, K., Wyckoff, S. N., Fallgatter, A. J., Ehlis, A., & Strehl, U. (2015). Neurofeedback as a nonpharmacological treatment for adults with attention-deficit/hyperactivity disorder (ADHD): Study protocol for a randomized controlled trial. Trials, 16, 1–14. doi:10.1186/s13063-015-0683-4.

    Article  Google Scholar 

  • Monastra, V. J., Lynn, S., Linden, M., Lubar, J. F., Gruzelier, J., & LaVaque, T. J. (2005). Electroencephalographic biofeedback in the treatment of attention-deficit/hyperactivity disorder. Applied Psychophysiology and Biofeedback, 30(2), 95–114.

    Article  PubMed  Google Scholar 

  • MTA Cooperative Group. (1999). A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder. Archives of General Psychiatry, 56(12), 1073–1086.

    Article  Google Scholar 

  • Nash, J. K. (2000). Treatment of attention deficit hyperactivity disorder with neurotherapy. Clinical Electroencephalography, 31(1), 30–37.

    Article  PubMed  Google Scholar 

  • Orlando, P. C., & Rivera, R. O. (2004). Neurofeedback for elementary students with identified learning problems. Journal of Neurotherapy, 8(2), 5–19. doi:10.1300/J184v08n02_02.

    Article  Google Scholar 

  • Othmer, S., Othmer, S. F., & Kaiser, D. A. (2000). EEG biofeedback: An emerging model for its global efficacy. In J. R. Evans & A. Abarbanel (Eds.), Introduction to quantitative EEG and neurofeedback (pp. 244–310). San Diego: Academic Press.

    Google Scholar 

  • Rossiter, T. (2004). The effectiveness of neurofeedback and stimulant drugs in treating AD/HD: Part II. Replication. Applied Psychophysiology and Biofeedback, 29(4), 233–243.

    Article  PubMed  Google Scholar 

  • Russell-Chapin, L., Kemmerly, T., Liu, W. C., Zagardo, M. T., Chapin, T., Dailey, D., & Dinh, D. (2013). The effects of neurofeedback in the default mode network: Pilot study results of medicated children with ADHD. Journal of Neurotherapy: Investigations in Neuromodulations, Neurofeedback and Applied Meuroscience, 17(1), 35–42. doi:10.1080/10874208.2013.759017.

    Article  Google Scholar 

  • Thompson, L., & Thompson, M. (1998). Neurofeedback combined with training in metacognitive strategies: Effectiveness in students with ADD. Applied Psychophysiology and Biofeedback, 23(4), 243–263.

    Article  PubMed  Google Scholar 

  • Toomim, H., Mize, W., Yeekwong, P., Toomim, M., Marsh, R., Kozlowski, G. P., & Remond, A. (2004). Intentional increase of cerebral blood oxygenation using hemoencephalography: An efficient brain exercise therapy. Journal of Neurotherapy, 8(3), 5–21. doi:10.1300/J184v08n03_02.

    Article  Google Scholar 

  • Wechsler, D. (2004). The Wechsler Intelligence Scale for Children (4th ed.). London: Pearson Assessment.

    Google Scholar 

  • Williams, J. R. (2008). Revising the declaration of Helsinki. World Medical Journal, 54, 120–125.

    Google Scholar 

  • Zuberer, A., Brandeis, D., & Drechsler, R. (2015). Are treatment effects of neurofeedback training in children with ADHD related to the successful regulation of brain activity? A review on the learning of regulation of brain activity and a contribution to the discussion on specificity. Frontiers in Human Neurocience, 27(9), 1–15. doi:10.3389/fnhum.2015.00135.

    Google Scholar 

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Correspondence to Paloma González-Castro.

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González-Castro, P., Cueli, M., Rodríguez, C. et al. Efficacy of Neurofeedback Versus Pharmacological Support in Subjects with ADHD. Appl Psychophysiol Biofeedback 41, 17–25 (2016). https://doi.org/10.1007/s10484-015-9299-4

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