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Longitudinal Trajectories of Alcohol Use in Vietnamese Adults with Hazardous Alcohol Use and HIV

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Abstract

A three-armed drinking cessation trial in Vietnam found that both a brief and intensive version of an intervention effectively reduced hazardous drinking in people living with HIV. We used group-based trajectory modeling (GBTM) to assess the extent to which findings may vary by latent subgroups distinguished by their unique responses to the intervention. Using data on drinking patterns collected over the 12 months, GBTM identified five trajectory groups, three of which were suboptimal [“non-response” (17.2%); “non-sustained response” (15.7%), “slow response” (13.1%)] and two optimal [“abstinent” (36.4%); “fast response” (17.6%)]. Multinomial logistic regression was used to determine that those randomized to any intervention arm were less likely to be in a suboptimal trajectory group, even more so if randomized to the brief (vs. intensive) intervention. Older age and higher baseline coping skills protected against membership in suboptimal trajectory groups; higher scores for readiness to quit drinking were predictive of it. GBTM revealed substantial heterogeneity in participants’ response to a cessation intervention and may help identify subgroups who may benefit from more specialized services within the context of the larger intervention.

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Data Availability

Requests for deidentified participant data can be submitted to vgo@live.unc.edu. Data will be made available to researchers whose proposed use of the data has been approved. These data may be used for replication of these study results and individual participant data meta-analysis. To obtain the data, investigators must submit a proposal describing the intended use of the data. The proposals will be reviewed by an independent review committee (that does not include any of the authors).

Code Availability

Requests for code can be submitted to smi00831@umn.edu.

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Acknowledgements

The authors would like to thank the study participants. We also thank Dr. Kimberly Powers for valuable input on earlier drafts of this manuscript.

Funding

Primary funding was obtained from the National Institute on Drug Abuse of the National Institutes of Health (Grant No. R01DA037440).

Author information

Authors and Affiliations

  1. School of Public Health, University of Minnesota, Twin Cities, 1300 2Nd Ave S, Suite 300, Minneapolis, MN, USA

    M. Kumi Smith & Eva A. Enns

  2. School of Public Health, Johns Hopkins University, Baltimore, MD, USA

    Carl A. Latkin & Constantine Frangakis

  3. School of Medicine, Johns Hopkins University, Baltimore, MD, USA

    Heidi E. Hutton

  4. School of Medicine, University of Washington, Seattle, WA, USA

    Geetanjali Chander

  5. School of Public Health, University of North Carolina, Chapel Hill, Chapel Hill, NC, USA

    Tran Viet Ha, Teerada Sripaipan & Vivian F. Go

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  1. M. Kumi Smith
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Contributions

All authors contributed to the study conception and design. VFG obtained funding and provided supervision of the study. VFG, HEH, GC, TS, and TVH provided administrative, technical, or material support for the study. VFG, HEH, TVH, GC, CAL, TS, and CF were responsible for the acquisition of data. MKS conducted the statistical analysis and drafted the initial draft. VFG, HEH, CAL, GC, EAE, TS, and CF provided critical revision of the manuscript for important intellectual content.

Corresponding author

Correspondence to M. Kumi Smith.

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Conflict of interest

The authors declare no conflicts of interest or competing interests.

Ethical Approval

The study protocol received ethical approval from the Institutional Review Boards at the University of North Carolina Gillings School of Global Public Health, the Johns Hopkins University Bloomberg School of Public Health, and the Thai Nguyen Center for Preventive Medicine.

Consent to Participate

All participants signed a written informed consent in Vietnamese prior to any study procedures.

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N/A.

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Smith, M.K., Latkin, C.A., Hutton, H.E. et al. Longitudinal Trajectories of Alcohol Use in Vietnamese Adults with Hazardous Alcohol Use and HIV. AIDS Behav 27, 1972–1980 (2023). https://doi.org/10.1007/s10461-022-03930-z

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