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The Role of Alcohol-Related Behavioral Research in the Design of HIV Secondary Prevention Interventions in the Era of Antiretroviral Therapy: Targeted Research Priorities Moving Forward

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Abstract

HIV secondary prevention focuses on averting onward HIV transmission, which can be realized when people living with HIV enact requisite HIV care continuum-related behaviors to achieve viral suppression, and engage in condom-protected sex when virally unsuppressed. Alcohol has been detrimentally linked to all aspects of HIV secondary prevention, and although a growing number of behavioral interventions account for and address alcohol use within this realm, further efforts are needed to fully realize the potential of such initiatives. The present article proposes a series of targeted priorities to inform the future design, implementation, and evaluation of alcohol-related behavioral intervention research within the scope of HIV secondary prevention. These priorities and corresponding approaches account for the challenges of resource-constrained clinic environments; capitalize on technology; and address key comorbidities. This framework provides the foundation for a range of alcohol-related behavioral interventions that could potentially enhance global HIV secondary prevention efforts in the years ahead.

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Acknowledgements

This manuscript was prepared in association with a grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA)/National Institutes of Health (NIH) (5U13AA024987-05, PI: Stephen Maisto, Ph.D.). Dr. Shuper’s related research is supported by a grant from the NIAAA/NIH (5UH2AA026212-02, PI: Paul Shuper, Ph.D.), and his salary is supported in part by the Ontario HIV Treatment Network (OHTN).

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  1. Institute for Mental Health Policy Research and Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), 33 Russell Street, Toronto, ON, M5S 2S1, Canada

    Paul A. Shuper

  2. Dalla Lana School of Public Health, University of Toronto, Toronto, Canada

    Paul A. Shuper

  3. Institute for Collaboration On Health, Intervention, and Policy (InCHIP), University of Connecticut, Storrs, CT, USA

    Paul A. Shuper

  4. Alcohol, Tobacco and Other Drug Research Unit, South African Medical Research Council, Pretoria, South Africa

    Paul A. Shuper

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Shuper, P.A. The Role of Alcohol-Related Behavioral Research in the Design of HIV Secondary Prevention Interventions in the Era of Antiretroviral Therapy: Targeted Research Priorities Moving Forward. AIDS Behav 25 (Suppl 3), 365–380 (2021). https://doi.org/10.1007/s10461-021-03302-z

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