Abstract
Cardiac arrhythmia relating to hypoglycemia is suggested as a cause of death in diabetic patients. This article introduces electrocardiographic (ECG) parameters for artificially induced hypoglycemia detection. In addition, a hybrid technique of swarm-based support vector machine (SVM) is introduced for hypoglycemia detection using the ECG parameters as inputs. In this technique, a particle swarm optimization (PSO) is proposed to optimize the SVM to detect hypoglycemia. In an experiment using medical data of patients with Type 1 diabetes, the introduced ECG parameters show significant contributions to the performance of the hypoglycemia detection and the proposed detection technique performs well in terms of sensitivity and specificity.
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Acknowledgments
This study was supported by a grant from the Juvenile Diabetes Research Foundation. The authors would like to thank Dr. Nejhdeh Ghevondian, and Assoc. Prof. Timothy Jones for their contribution.
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The authors have no conflict of interest related to this study and the manuscript presented in this article.
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Associate Editor Leonidas D. Iasemidis oversaw the review of this article.
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Nuryani, N., Ling, S.S.H. & Nguyen, H.T. Electrocardiographic Signals and Swarm-Based Support Vector Machine for Hypoglycemia Detection. Ann Biomed Eng 40, 934–945 (2012). https://doi.org/10.1007/s10439-011-0446-7
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DOI: https://doi.org/10.1007/s10439-011-0446-7