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Ultrasound diagnosis of pancreatic solid tumors

  • Special Feature: Review Article
  • Ultrasonographic diagnosis of pancreatic diseases-This is all you need
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Abstract

Introduction

Advances and widespread use of various diagnostic imaging modalities have dramatically improved our ability to visualize and diagnose pancreatic diseases. In particular, ultrasonography in pancreatic diseases plays an important role from screening to diagnosis as a simple and safe examination method.

Methods

The basic scanning method of transabdominal pancreatic ultrasonography, characterization, and differential diagnosis by ultrasonography including contrast-enhanced ultrasonography (CEUS) for solid pancreatic tumors are reviewed with reference to various papers.

Results

In recent years, the ability to visualize and diagnose pancreatic mass lesions has been dramatically improved with advances in ultrasound equipment. In particular, CEUS using an ultrasound contrast agent has made it possible to evaluate hemodynamics in organs or lesions as well as in the flow signal of arterial blood vessels, and it has played an important role not only in diagnosis of the presence of a lesion but also in the qualitative diagnosis. The enhancement behavior and pattern with CEUS of pancreatic solid tumors is shown in text and Fig. 9. Moreover, the flow chart for diagnosing pancreatic solid tumors with CEUS classifying the enhancement behavior and pattern for pancreatic solid tumors on CEUS is shown (Fig. 10). In meta-analyses, the pooled sensitivity in the differential diagnosis of pancreatic adenocarcinomas and other pancreatic focal masses with CEUS was 86–90%, and the pooled specificity was 75–88%.

Conclusion

CEUS is a minimally invasive and useful diagnostic method that can be used to make a simple and quick qualitative diagnosis of pancreatic diseases. CEUS provides a lot of information important for diagnosis, and has led to changes in the conventional diagnostic systems in pancreatic diseases.

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Abbreviations

US:

Ultrasonography

THI:

Tissue harmonic imaging

CEUS:

Contrast-enhanced ultrasonography

CECT:

Contrast-enhanced computed tomography

SPV:

Superior mesenteric vein

SMA:

Superior mesenteric artery

AP:

Acute pancreatitis

CP:

Chronic pancreatitis

AIP:

Autoimmune pancreatitis

PC:

Pancreatic cancer

MFP:

Mass-forming pancreatitis

PNET:

Pancreatic neuroendocrine tumor

SPN:

Solid pseudopapillary neoplasm

EFSUMB:

The European Federation of Societies for Ultrasound in Medicine and Biology

PAMUS:

Pancreatic Multicenter Ultrasound Study

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Authors and Affiliations

  1. Department of Gastroenterology and Hepatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan

    Atsushi Sofuni, Takayoshi Tsuchiya & Takao Itoi

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  1. Atsushi Sofuni
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  2. Takayoshi Tsuchiya
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  3. Takao Itoi
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Correspondence to Atsushi Sofuni.

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Sofuni, A., Tsuchiya, T. & Itoi, T. Ultrasound diagnosis of pancreatic solid tumors. J Med Ultrasonics 47, 359–376 (2020). https://doi.org/10.1007/s10396-019-00968-w

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