Skip to main content
Log in

Utility of Valsalva maneuver in the endoscopic pharyngeal observation

  • Original Article
  • Published:
Esophagus Aims and scope Submit manuscript

Abstract

Background

Metachronous cancer rate in the pharynx is high before and after the treatment of esophageal cancer. Endoscopic observation is difficult in the pharynx especially in the postcricoid area. Pharyngeal cancer in the postcricoid area has been often found in advanced stage. Valsalva maneuver has been reported to improve the visibility.

Methods

From May 2017 we introduced a dedicated mouthpiece to conduct Valsalva maneuver. One hundred consecutive patients who had been observed throughout the pharynx by one endoscopist were enrolled. A total of 200 image files before and after introduction were made and reviewed by three endoscopists. We retrospectively evaluated the utility and safety of Valsalva maneuver.

Results

The visibility before introduction was Good in three cases, Moderate in 12 cases and Poor in 85 cases. Meanwhile, the visibility after introduction was Good in 58 cases, Moderate in 23 cases, and Poor in 19 cases (P < 0.05). Nine lesions including hypopharyngeal cancer were found and adverse events were not observed in this study.

Conclusion

The Valsalva maneuver was considered to be a safe and effective method in endoscopic observation of the pharynx.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Wahlberg PC, Andersson KE, Bi€orklund AT, M€oller TR. Carcinoma of the hypopharynx: analysis of incidence and survival in Sweden over a 30-year period. Head Neck. 1998;20:714–9.

    Article  CAS  Google Scholar 

  2. Eckel HE, Staar S, Volling P, Sittel C, Damm M, Jungehuelsing M. Surgical treatment for hypopharynx carcinoma: feasibility, mortality, and results. Otolaryngol Head Neck Surg. 2001;124:561–9.

    Article  CAS  Google Scholar 

  3. Muto M, Minashi K, Yano T, et al. Early detection of superficial squamous cell carcinoma in the head and neck region and esophagus by narrow band imaging: a multicenter randomized controlled trial. J Clin Oncol. 2010;28:1566–72.

    Article  Google Scholar 

  4. Iizuka T, Kikuchi D, Hoteya S, et al. Clinical advantage of endoscopic submucosal dissection over endoscopic mucosal resection for early mesopharyngeal and hypopharyngeal cancers. Endoscopy. 2011;43:839–43.

    Article  CAS  Google Scholar 

  5. Iizuka T, Kikuchi D, Hoteya S, Yahagi N, Takeda H. Endoscopic submucosal dissection for treatment of mesopharyngeal and hypopharyngeal carcinomas. Endoscopy. 2009;41:113–7.

    Article  CAS  Google Scholar 

  6. Kato M, Hayashi Y, Takehara T. Valsalva maneuver to visualize the closed hypopharyngeal space during transoral endoscopy using a novel dedicated mouthpiece. Dig Endosc. 2019;31:e24–e2525.

    PubMed  Google Scholar 

  7. Kato M, Ishihara R, Hamada K, et al. Endoscopic surveillance of head and neck cancer in patients with esophageal squamous cell carcinoma. Endosc Int Open. 2016;4:e752–e755755.

    Article  Google Scholar 

  8. Katada C, Yokoyama T, Yano T, et al. Alcohol consumption and multiple dysplastic lesions increase risk of squamous cell carcinoma in the esophagus, head, and neck. Gastroenterology. 2016;151:860–9.

    Article  CAS  Google Scholar 

  9. Rodrigues J, Breda E, Monteiro E. Surgically-treated locoregionally advanced hypopharyngeal cancer: outcomes. Int Arch Otorhinolaryngol. 2018;22:443–8.

    Article  Google Scholar 

  10. Kadapa N, Mangale K, Watve P, Rao SLM, Raju AK, Subramanyeshwar RT. Postcricoid carcinoma: is organ preservation justified in T3? Laryngoscope. 2015;125:356–9.

    Article  Google Scholar 

  11. Murono S, Tsuji A, Endo K, Kondo S, Wakisaka N, Yoshizaki T. Evaluation of modified Killian’s method: a technique to expose the hypopharyngeal space. Laryngoscope. 2014;124:2526–30.

    Article  Google Scholar 

  12. Sakai A, Okami K, Sugimoto R, et al. A new technique to expose the hypopharyngeal space: the modified Killian’s method. Auris Nasus Larynx. 2014;41:207–10.

    Article  Google Scholar 

  13. Freeman SR, Keith AO, Aucott W, Kazmi N, Nigam A. Comparison between two valsalva techniques for improvement of hypopharyngeal nasendoscopy: a preliminary communication. Clin Otolaryngol. 2007;32:488–91.

    Article  CAS  Google Scholar 

  14. Hamada K, Ishihara R, Yamasaki Y, et al. Transoral endoscopic examination of head and neck region. Dig Endosc. 2018;30:516–21.

    Article  Google Scholar 

  15. Yamasaki Y, Ishihara R, Hamada K. Usefulness of the Valsalva maneuver without a mouthpiece to observe the hypopharynx using transoral endoscopy. Dig Endosc. 2017;29:643–4.

    Article  Google Scholar 

  16. Tanaka T, Niwa Y, Tajika M, et al. Prospective evaluation of a transnasal endoscopy utilizing flexible spectral imaging color enhancement (FICE) with the Valsalva maneuverfor detecting pharyngeal and esophageal cancer. Hepatogastroenterology. 2014;61:1627–34.

    CAS  PubMed  Google Scholar 

  17. Kikuchi D, Iizuka T, Yamada A, et al. Utility of magnifying endoscopy with narrow band imaging in determining the invasion depth of superficial pharyngeal cancer. Head Neck. 2015;37:846–50.

    Article  Google Scholar 

  18. Iwatsubo T, Ishihara R, Nakagawa K et al. Pharyngeal observation via transoral endoscopy using a lip cover type mouthpiece. J Gastroenterol Hepatol. 2018. (Epub ahead of print).

  19. Park JH, Sagong M, Chang W. Valsalva retinopathy following esophagogastroduodenoscopy under propofol sedation: a case report. World J Gastroenterol. 2014;20:3056–8.

    Article  Google Scholar 

  20. Kilincalp S, Çoban Ş, Yüksel I. An alarming condition after upper gastrointestinal endoscopy: valsalvaretinopathy. Gastroenterol Nurs. 2013;36:465–6.

    Article  Google Scholar 

  21. Yamasaki Y, Ishihara R, Hanaoka N, et al. Pethidine hydrochloride is a better sedation method for pharyngeal observation by transoral endoscopy compared with no sedation and midazolam. Dig Endosc. 2017;29:39–48.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Daisuke Kikuchi.

Ethics declarations

Ethical Statement

The study protocol was approved by the Institutional Review Board of Toranomon hospital. In this retrospective study, only anonymous data was used, so provision of informed consent was waived.

Conflict of interest

All authors declare that there are no conflicts of interest.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kikuchi, D., Tanaka, M., Suzuki, Y. et al. Utility of Valsalva maneuver in the endoscopic pharyngeal observation. Esophagus 17, 323–329 (2020). https://doi.org/10.1007/s10388-020-00722-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10388-020-00722-z

Keywords